When examined by fluorescence microscopy the rabbit basilar artery contains a rich adrenergic-like plexus at the adventitiomedial junction. The fluorescence disappears upon chronic reserpinization and bilateral superior cervical ganglionectomy. Transmural stimulation of intramural nerves a results in a response which is predominantly constrictor but also contains a small, inconstant dilator com...

murmur was present. The breath sounds were poor and bowel sounds were audible in the left chest. The abdomen was scaphoid and the liver was not palpable. There was hypoplasia of the left arm and hand with a contracture of the left axilla. Chest roentgenogram revealed the presence of the liver and bowel loops in the left chest. The baby was intubated and placed on a respirator in 100 percent 02....

Anatomical and pharmacological evidence suggests a role for catecholamines (CAs) in the modulation of the baroreceptor reflex within the nucleus tractus solitarii (NTS). Single neurons in the NTS of the rat were studied for their responses to activation of the baroreceptor reflex and to iontophoretic administration of dopamine, norepinephrine (NE), and epinephrine (EPI) to determine the relatio...

OBJECTIVE In this work, role of the adrenergic nerve system (alpha1 and beta2) in adjustment of the bronchomotor tonus in healthy people was researched. METHODS Parameters of the lung function are determined by Body plethysmography. Raw and ITGV were registered and SRaw was calculated as well. Aerosolization is done with standard aerosolizing machines - Asema. RESULTS Results gained shows t...

1. Intact mouse neuroblastoma NS20 cells, in the presence of cyclic adenosine 3':5'-monophosphate (cAMP) phosphodiesterase inhibitor, responded to adenosine (200 muM) and 2-chloroadenosine (200 muM) with a 20-fold increase in intracellular cAMP levels. AMP (200 muM) additions caused only a 3.5-fold cAMP level elevation. ATP, ADP, guanosine, cytidine, uridine, and guanine, all at 200 muM, had no...

島本 暉朗 ・松尾 高明 ・服部 圭佑 ・本庄 俊 The intravenous injection of 0.5 to 3.0 mg/kg of traps-2-phenylcyclopropylamine maleate (SKF-385) in the anesthetized dog produces the pressor effect which is prevented by the adrenolytic doses of tolazoline and dibenamine (1). However, the repetition of the doses of SKF-385 exerts the depressor effect which is totally abolished by the pretreat ment with reserpine. The...

Planula larvae of Halocordyle disticha were examined for the presence of catecholamines using a multipronged approach. Transmission electron micrographs of planular sensory cells and ganglionic cells demonstrated dense-cored vesicles and electron-dense droplets in both cell types. These vesicles and droplets were similar in morphology to catecholamine-containing granules of vertebrates. Planula...

Eight of nine newborn infants with severe persistent pulmonary hypertension of the newborn (PPHN), and a predicted mortality of 100%, and one infant with a predicted mortality >94% based on alveolar-arterial oxygen tension difference ((A-a)Do2) were treated with magnesium sulphate (MgSO4) as a life saving therapy after they failed to improve with conventional treatment. Magnesium at high serum ...