BACKGROUND Considering the increasing trend of obesity reported in current data, this study was conducted to examine trends of obesity and abdominal obesity among Tehranian adults during a median follow-up of 6.6 years. METHODS Height and weight of 4,402 adults, aged 20 years and over, participants of the Tehran Lipid and Glucose Study (TLGS), were measured in 1999-2001(phase I) and again in ...

BACKGROUND Although current data shows a positive association between obesity and development of coronary heart disease (CHD) in general population, there is limited data on the important protective role of central or general obesity in patients with prevalent CHD or the "obesity paradox", from this region. OBJECTIVES The objective of the present investigation was to describe the relationship...

OBJECTIVE To investigate the association between changes in fasting plasma glucose (FPG) values and incident type 2 diabetes (T2D) in a cohort of the Iranian population. DESIGN Prospective cohort study. SETTING This study was conducted within the framework of the Tehran Lipid and Glucose Study (TLGS) to investigate the association between change in FPG between baseline examination (1999-200...

OBJECTIVE The aim of this study was to evaluate the validity of cause of death stated in death certificates in Tehran using outcome measures of the Tehran Lipid and Glucose Study (TLGS), an ongoing prospective cohort study. METHODS The cohort was established in 1999 in a population of 15005 people, 3 years old and over, living in Tehran; 3551 individuals were added to this population three ye...

BACKGROUND General and abdominal obesity are major global health problems. This cross-sectional study was conducted to evaluate the association between consumption of sugar-sweetened beverages (SSBs) and body mass index and waist circumference status in 5852 Iranian adults within the framework of the Tehran Lipid and Glucose Study (TLGS). METHODS Intakes of SSBs including carbonated drinks an...

BACKGROUND Given the lack of data clarifying the manner in which women with metabolic syndrome (MetS) in different eras of their life perceive their health-related quality of life (HRQoL), this study aimed at investigating the association between MetS and HRQoL in reproductive age and post menopausal women. METHODS This was a cross-sectional study conducted within the framework of Tehran Lipi...

We examined the cholesteryl ester transfer protein (CETP) gene TaqI intron 1 B1/B2 polymorphism and the -629A/C CETP promoter polymorphism in respect to high-density lipoprotein cholesterol (HDL-C) in a healthy Iranian population taken from the Tehran Lipid and Glucose Study (TLGS). The relationship between CETP activity and HDL-C level was also determined along with body mass index, blood pres...

BACKGROUND Adherence to the Mediterranean diet (MedDiet) has been proposed to reduce the risk of metabolic syndrome (MetS), but the association of the diet on MetS in non-Mediterranean populations remains unclear. OBJECTIVES The aim of this study was to investigate whether adherence to the MedDiet is related to the incident MetS and its components during a 3-year follow-up among Iranian adult...

Background The aim of this study was to determine the incidence and prevalence of obesity in Tehranian children. Methods Data from children participated in Tehran Lipid and Glucose Study (TLGS) were evaluated. Cut off points for definition of obesity was the CDC's standard thresholds of the 95th percentile and 85th percentile for overweight. Prevalence, annual incidence of obesity, cumulative...