BACKGROUND Dose assessment using proper dosimeters is especially important in radiation protection optimization and imaging justification in diagnostic radiology. OBJECTIVE The aim of this study is to obtain the Entrance Skin Dose (ESD) of patients undergoing lumbar spine imaging using two thermoluminescence dosimeters TLD-100 (LiF: Mg, Ti) and GR-200 (LiF: Mg, Cu, P) and also to obtain the a...

Drosophila metalloproteinase Tolloid (TLD) is responsible for cleaving the antagonist Short gastrulation (SOG), thereby regulating signaling by the bone morphogenetic protein (BMP) Decapentaplegic (DPP). In mice there are four TLD-related proteinases, two of which, BMP1 and mammalian Tolloid-like 1 (mTLL1), are responsible for cleaving the SOG orthologue Chordin, thereby regulating signaling by...

Inhibition of DNA replication with hydroxyurea during thymine starvation of Escherichia coli shows that active DNA synthesis is not required for thymineless death (TLD). Hydroxyurea experiments and thymine starvation of lexA3 and uvrA DNA repair mutants rule out unbalanced growth, the SOS response, and nucleotide excision repair as explanations for TLD.

BACKGROUND Parasympathetic pulmonary nerves release acetylcholine that induces smooth muscle constriction. Disruption of parasympathetic pulmonary nerves improves lung function and COPD symptoms. AIMS To evaluate 'targeted lung denervation' (TLD), a novel bronchoscopic therapy based on ablation of parasympathetic pulmonary nerves surrounding the main bronchi, as a potential therapy for COPD. ...

Introduction: Nasopharyngeal carcinoma is one of the most common malignancies in the head and neck region and radiotherapy is its treatment of choice. In spite of the fact that it is widely used, due to the presence of many sensitive organs or tissues in this region, patients may suffer from a wide range of side effects. One such sensitive tissue is the spinal cord. If the absorbed dose to spin...

The paper presents a high sensitivity TLD system, designed for the survey of the environmental radioactivity. It is based on the use of TL detectors type LiF:Mg, Cu, P, commercially known as GR-200A. The dosimeter designed in our Institute, contains 3 detectors, and the measurement value is calculated as the arithmetic mean. A very sensitive, TL Reader, READER ANALYSER RA’94 was chosen and an o...

Context: Test-Driven development (TDD) is a software development approach where test cases are written before actual development of the code in iterative cycles. TDD has gained attention of many software practitioners during the last decade since it has suggested several benefits in the software development process. However, empirical evidence of its dominance in terms of internal code quality,...

Methods: Eight patients treated using the CyberKnife were selected for this study. Organs at risk and target were delineated on volumetric CT data and treatment planning (Multiplan v.4.5.0) was optimized accordingly, in order to achieve the required prescribed target dose and critical structures sparing for each patient. The final treatment plan, consisted from a set of non-isocentric and non-c...

INTRODUCTION The angular dependency of response for TLD cards may cause deviation from its true value on the results of environmental dosimetry, since TLDs may be exposed to radiation at different angles of incidence from the surrounding area. OBJECTIVE A 3D setting of TLD cards has been calibrated isotropically in a standard radiation field to evaluate the improvement of the accuracy of meas...

The Thermoluminescence Personal Dosimetry Laboratory of the University of Costa Rica provides dose measurements for around 90% of occupational radiation workers in the country. The assessment of doses to workers routinely exposed to external sources of radiation constitutes an integral part of any radiation protection programme and helps national authorities to ensure acceptably safe and satisf...