BMP signaling is modulated by a number of extracellular proteins, including the inhibitor Chordin, Tolloid-related enzymes (Tld), and the interacting protein Twisted Gastrulation (Tsg). Although in vitro studies have demonstrated Chordin cleavage by Tld enzymes, its significance as a regulatory mechanism in vivo has not been established in vertebrates. In addition, Tsg has been reported in diff...

BACKGROUND Dose assessment using proper dosimeters is especially important in radiation protection optimization and imaging justification in diagnostic radiology. OBJECTIVE The aim of this study is to obtain the Entrance Skin Dose (ESD) of patients undergoing lumbar spine imaging using two thermoluminescence dosimeters TLD-100 (LiF: Mg, Ti) and GR-200 (LiF: Mg, Cu, P) and also to obtain the a...

Drosophila metalloproteinase Tolloid (TLD) is responsible for cleaving the antagonist Short gastrulation (SOG), thereby regulating signaling by the bone morphogenetic protein (BMP) Decapentaplegic (DPP). In mice there are four TLD-related proteinases, two of which, BMP1 and mammalian Tolloid-like 1 (mTLL1), are responsible for cleaving the SOG orthologue Chordin, thereby regulating signaling by...

PURPOSE Analyze the characteristics of TLD LiF-100 powder between multiple LiF crystal batches. METHODS The RPC used TLD LiF-100 encapsulated powder to verify the output for photon and electron beams for 4 to 23 MV X-ray beams and 6 to 23 MeV electron beams, respectively, from the past 15 years. During that time period, the RPC commissioned more than 15 batches of TLD powder. Commissioning of...

Drisko proved that 2n−1 matchings of size n in a bipartite graph have rainbow matching n. For general graphs it is conjectured 2n suffice for this purpose (and when even). The known showing sharpness conjecture even are called badges. We improve the previously best bound from 3n−2 to 3n−3, using new line proof involves analysis appearance also prove “cooperative” generalization: t>0 and n≥3, an...

This paper proposes a study of the use of badges in the educational planning through the instructional design, in a codesign approach. Here are presented the concepts of this intersection and described the procedures and the analysis of an exploratory experiment involving the using of these concepts. It was observed that the using of codesign and the badges contributed to the creativity of the ...

Inhibition of DNA replication with hydroxyurea during thymine starvation of Escherichia coli shows that active DNA synthesis is not required for thymineless death (TLD). Hydroxyurea experiments and thymine starvation of lexA3 and uvrA DNA repair mutants rule out unbalanced growth, the SOS response, and nucleotide excision repair as explanations for TLD.

BACKGROUND Parasympathetic pulmonary nerves release acetylcholine that induces smooth muscle constriction. Disruption of parasympathetic pulmonary nerves improves lung function and COPD symptoms. AIMS To evaluate 'targeted lung denervation' (TLD), a novel bronchoscopic therapy based on ablation of parasympathetic pulmonary nerves surrounding the main bronchi, as a potential therapy for COPD. ...