TRANSFER RNA DYNAMICS AND TRANSFER-MESSENGER RNAACCOMMODATION IN BACTERIAL RIBOSOMES AT THE SINGLE-MOLECULELEVEL byMAY DAHERDecember 2012Advisor: Dr. David RuedaMajor: Chemistry (Biochemistry)Degree: Doctor of PhilosophySingle-molecule spectroscopy, protein-induced fluorescence enhancement(PIFE), fluorescence resonance energy transfer (FRET), and several ...

The purpose of this study was to determine the dose to the contralateral breast during accelerated partial breast irradiation (APBI) and to compare it to external beam-published values. Thermoluminescent dosimeter (TLD) packets were used to measure the dose to the most medial aspect of the contralateral breast during APBI simulation, daily quality assurance (QA), and treatment. All patients in ...

In immunocompetent individuals, the stability of the herpesvirus-host balance limits opportunities to study the disappearance of a virus-specific CD8(+) T-cell response. However, we noticed that in HLA-A 0201-positive infectious mononucleosis (IM) patients undergoing primary Epstein-Barr virus (EBV) infection, the initial CD8 response targets three EBV lytic antigen-derived epitopes, YVLDHLIVV ...

DNS is a critical infrastructure of the global Internet. To assure DNS’s efficient and robust operations, each domain, especially each of the Top-Level-Domains (TLDs), should deploy multiple redundant nameservers in diverse locations. To assess the robustness of TLD nameserver deployment regarding the nameserver redundancy and location diversity, we conduct a measurement study by sending specia...

BACKGROUND The narrative abilities provide valuable information about the linguistic, cognitive and social development of school-age children with typical language development (TLD). AIM To examine the temporal ordering of figures and the narrative abilities of school-age children with TLD in relation to the type of discourse presented. METHOD Participants of this study included 60 children...

Dorsal cell fate in Drosophila embryos is specified by an activity gradient of Decapentaplegic (Dpp), a homologue of bone morphogenetic proteins (Bmps) 2/4. Previous genetic and biochemical studies have revealed that the Sog, Tsg and Tld proteins modify Dpp activity at the post-transcriptional level. The predominant view is that Sog and Tsg form a strong ternary complex with Dpp that prevents i...

BACKGROUND Industrial radiography is known to be one of the most vulnerable lines of work among the range of different radiation work. According to the relevant law in Korea, every worker registered in this work should check their blood cell counts every year in addition to their thermoluminescent dosimeter (TLD) doses. Since the law was enacted, however, few follow-up studies have been carried...

BMP signaling is modulated by a number of extracellular proteins, including the inhibitor Chordin, Tolloid-related enzymes (Tld), and the interacting protein Twisted Gastrulation (Tsg). Although in vitro studies have demonstrated Chordin cleavage by Tld enzymes, its significance as a regulatory mechanism in vivo has not been established in vertebrates. In addition, Tsg has been reported in diff...

Drosophila metalloproteinase Tolloid (TLD) is responsible for cleaving the antagonist Short gastrulation (SOG), thereby regulating signaling by the bone morphogenetic protein (BMP) Decapentaplegic (DPP). In mice there are four TLD-related proteinases, two of which, BMP1 and mammalian Tolloid-like 1 (mTLL1), are responsible for cleaving the SOG orthologue Chordin, thereby regulating signaling by...

Introduction: In radiation therapy, knowing the dose rates to healthy organs and tumors is beneficial, and thermoluminescent dosimeter (TLD) allows for this possibility. This study was aimed at determining the dose-response differences of TLDs in various types of radiation, energy levels, and dose rate calibrated with other types of radiation beams and energy and dose levels. Materials and Meth...