OBJECTIVES To quantify the improvement in health outcomes in patients after total knee replacement (TKR). METHODS This was a two-year non-randomized prospective observational study in knee osteoarthritis (OA) patients undergone TKR. Patients were interviewed one week before, six months after, and two years after surgery using a standardized questionnaire including the SF-36, the Oxford Knee S...

OBJECTIVES To evaluate bleeding and the estimated blood loss in patients who underwent total knee replacement (TKR) with different closed suction drains (3.2-mm and 4.8-mm gauge). METHODS This was a randomized controlled trial with 22 patients who underwent TKR and were divided into two groups: Group I, with 11 patients in whom the 3.2-mm suction drain was used, and Group II, with 11 patients...

What is the measure of its success? Total knee replacements (TKRs) are increasing throughout the developed world. More than 600 000 primary TKRs were performed in the USA in 2009, with >95% of these done on people with advanced knee OA [1]. The use of TKRs is increasing especially in individuals <65 years of age [1], who have less functional impairment than their older counterparts [2]. Althoug...

Every year, thousands of patients suffer from joint diseases, such as rheumatoid arthritis or osteoarthritis, and need total knee replacement (TKR) surgery to recover their normal functions. Presently, the positioning of prosthetic components in surgeries mainly depends on clinic experiences of doctors and special surgical guiding devices. To avoid the limitations of jig-based TKR systems, we d...

BACKGROUND The aim of this study was to assess the safety and efficacy of switching therapy from low molecular weight heparin (LMWH; enoxaparin) to dabigatran for prevention of venous thromboembolic events (VTE) in patients undergoing elective total hip or knee replacement surgery (THR/TKR). METHODS This was a prospective, multicenter, open-label, single-arm, observational, study in patients ...

BACKGROUND Total knee replacement (TKR) or unicompartmental knee replacement (UKR) are options for end-stage osteoarthritis. However, comparisons between the two procedures are confounded by differences in baseline characteristics of patients undergoing either procedure and by insufficient reporting of endpoints other than revision. We aimed to compare adverse outcomes for each procedure in mat...

BACKGROUND In previous studies, 50%-70% of patients referred to orthopedic surgeons for total knee replacement (TKR) were not surgical candidates at the time of initial assessment. The purpose of our study was to identify and cross-validate patient self-reported predictors of suitability for TKR and to determine the clinical utility of a predictive model to guide the timing and appropriateness ...

OBJECTIVE To estimate the impact of NICE approval of tumor necrosis factor inhibitor (TNFi) therapies on the incidence of total hip replacement (THR) and total knee replacement (TKR) among rheumatoid arthritis (RA) patients in England and Wales. METHODS Primary care data [Clinical Practice Research Datalink (CPRD)] for the study period (1995-2014) were used to identify incident adult RA patie...

BACKGROUND Venous thromboembolism is a common, fatal, and costly injury which complicates major surgery in older adults. The American College of Chest Physicians recommends high potency prophylaxis regimens for individuals undergoing total hip or knee replacement (THR or TKR), but surgeons are reluctant to prescribe them due to fear of excess bleeding. Identifying a high risk cohort such as old...

BACKGROUND Limited previous findings have detailed biomechanical advantages following implantation with mobile bearing (MB) prostheses after total knee replacement (TKR) surgery during walking. The aim of this study was to compare three dimensional spatiotemporal, kinematic, and kinetic parameters during walking to examine whether MBs offer functional advantages over fixed bearing (FB) designs....