Human tissue has been stored and used for research on a regular basis for more than 80 years. During the 1990s, collections of human tissue suddenly became framed as ethical problems in a process reflecting developments in genetic research intertwined with developments in patient rights and steps towards increased commercialization of research. This review describes the process of framing tissu...

This document provides the latest recommendations for evaluation of potential sperm, oocyte, and embryo donors as well their recipients, incorporating recent information about optimal screening testing sexually transmitted infections, genetic diseases, psychological assessments. revised incorporates from US Centers Disease Control Prevention, Food Drug Administration, American Association Tissu...

Tissue engineering is a promising strategy for the reconstruction of auricles microtia patients. However, high number cells required successful application these methods. Since only small cell numbers can be isolated from perichondrium, must propagated over several passages in culture. little known about effects culture on perichondrocytes (PCs). In this study, PCs patients were analysed with r...

background and aims: cytomegalovirus (cmv) has worldwide distribution, and its prevalence rate depends on factors such as economic and geographical conditions. an important way of the virus transmission is via blood. due to high prevalence of anti-cmv antibodies in blood donors and lack of data concerning its seroprevalence in the region, this study was carried out to determine the prevalence r...

: Human adipose stem cells (hASCs) are an attractive cell source for bone tissue engineering applications. However, a critical issue to be addressed before widespread hASC clinical translation is the dramatic variability in proliferative capacity and osteogenic potential among hASCs isolated from different donors. The goal of this study was to test our hypothesis that electrical cell-substrate ...

In this study, our aim was to produce a generation of GMP-grade adipose tissue-derived mesenchymal stem cells for clinical applications. According to our results, we fulfill to establish consistent and also reproducible current good manufacturing practice (cGMP) compliant adipose tissue-derived mesenchymal stem cells from five female donors. The isolated cells were cultured in DMEM supplemented...

We have used a primary cloning assay to determine the frequency of 6-thioguanine (TG)-resistant tubular epithelial cells in kidney tissue from 72 human donors ranging in age from 2 to 94 years. The frequency of TG-resistant mutants ranged from approximately 5 x 10(-5) for donors in the first decade of life to approximately 2.5 x 10(-4) for donors in the eighth and later decades of life. Two dif...

introduction: iron deficiency anemia is an important limiting factor for the number of donations in regular donors. limited data is available on the iron status in iranian donors. this study was conduced to evaluate the prevalence of iron deficiency and its related factors in blood donors at shiraz blood transfusion centre in 2005. methods: this descriptive study was done on all blood donors wh...