BACKGROUND Elevation of the white blood cell (WBC) count during acute myocardial infarction (AMI) is associated with adverse outcomes. We examined the relationship between the WBC count and angiographic findings to gain insight into this relationship. Results and Methods-We evaluated data from 975 patients in the Thrombolysis In Myocardial Infarction (TIMI) 10A and 10B trials. Patients with a c...

BACKGROUND No previous study has assessed the possible role of dipyridamole for treatment of no-reflow during acute myocardial infarction (AMI). METHODS AND RESULTS Forty-six consecutive patients (age 64 ± 13 years, 37 men) with no reflow during primary percutaneous coronary intervention were randomized to initial treatment with either dipyridamole (0.56 mg/kg i.c.) or verapamil (1 mg i.c.). ...

AIM Myocardial contrast echocardiography (MCE) is effective in predicting myocardial viability and functional recovery on a segmental level in patients with acute myocardial infarction (AMI). In this study, we investigated whether insufficient myocardial reperfusion plays an important role in left ventricular (LV) remodeling and functional recovery in patients with thrombolysis in myocardial in...

AIMS To investigate the association between neutrophil count, outcomes, and benefit of clopidogrel therapy in ST-elevation myocardial infarction (STEMI). METHODS AND RESULTS Baseline neutrophil count was measured in 2865 patients in CLARITY-TIMI 28, a randomized trial of clopidogrel vs. placebo in STEMI patients undergoing fibrinolysis. Angiography was performed at 2-8 days following enrollme...

PURPOSE While both first-pass perfusion and late gadolinium enhancement by cardiovascular magnetic resonance (CMR) can assess coronary microvascular status in acute myocardial infarction (AMI), there are only limited data on their respective diagnostic utility. We aim to evaluate: the utility of first-pass perfusion and late gadolinium enhancement imaging in the detection and quantification of ...

results mean age of patients was 59.47 (sd = 12.48) years, of which 75 (75.8%) were male and 24 (24.2%) were female. based on univariable analysis, white blood cell (wbc) count, pain duration, lv function, maximal st-change, thrombus grade and eccentricity were identified as predictors of the no-reflow phenomenon. after multivariable logistic regression: wbc count and thrombus grade remained th...

introduction:patients with the coronary slow flow phenomenon (scf) frequently experience angina episodes. the purpose of this study was to determine efficacy of nicorandil in myocardial perfusion in patients with scf. methods: twenty patients (50.85 ± 12.96 y) with scf were studied.  we evaluate coronary slow flow according to protracted thrombolysis in myocardial infarction (timi) frame count....