BACKGROUND AND PURPOSE Results of our recent pilot clinical trial suggest that the efficacy of thrombolytic therapy in acute ischemic stroke may be enhanced by the coadministration of high-dose albumin. Here, we explored the microvascular hemodynamic effects of this combined therapy in a laboratory model of cortical arteriolar thrombosis. METHODS We studied the cortical microcirculation of ph...

introduction left atrial thrombi are present in one third of patients with severe rheumatic mitral stenosis and atrial fibrillation. a left atrial mass can be diagnosed as a thrombus by transthoracic echocardiography in the presence of the predisposing factors for a thrombus such as mitral stenosis and atrial fibrillation. the sensitivity of transthoracic echocardiography for detecting left atr...

A man showed a 90% narrowing at the origin of a saphenous vein graft (SVG) 6 years after bypass surgery. After 4 days of intravenous thrombolytic therapy the narrowing in the SVG disappeared completely. Thus, late stenosis of SVG can be caused by thrombosis not superimposed on organic narrowing.

INTRODUCTION Prosthetic valve thrombosis is a rare but life-threatening condition that requires careful evaluation and prompt treatment. While surgical intervention remains the gold standard, thrombolytic therapy is now emerging as a potential substitute. Various thrombolytic treatments including streptokinase, urokinase and recombinant tissue plasminogen activators have been reported with vari...

pulmonary thromboembolism (pte) has a wide spectrum of presentations, and its c ardinal manifestations include chest pain, dyspnea, and syncope. syncope as an initial presentation of pte occurs in 10-14% of patients and is not restricted to massive ptes. it can also occur in the setting of non- massive cases probably due to a vasovagal mechanism or the occurrence of conduction disturbances in p...

a 20-year-old woman was admitted to a gynecology hospital in her 6th month of pregnancy for high blood pressure and tonic-clonic seizure. primary diagnosis was eclampsia, and for that reason she underwent cesarean section. she also had headache on frontal and parietal areas without nausea or vomiting. there was not a focal neurological sign. rheumatology consultation was requested. systemic lup...

The author has described modern thrombolytic therapy of arterial and venous thrombosis and emboli by therapeutic fibrinolysis and other drugs also methods and effects of local and parenteral application of fibrinolysin preparations, dosage, control, indications. Contraindications, side-effects and their treatment with fibrinolysin antagonists and therapy with fibrinolysin combined with anticoag...

Patients with pulmonary thromboembolism (PE) often decompensate suddenly, and once hemodynamic compromise has developed, mortality is extremely high. Currently, thrombolytic therapy for PE is still controversial. We retrospectively evaluated 34 patients with PE between January 2010 and December 2013 in the Department of Pulmonary Medicine, Medical Park Samsun Hospital, Samsun, Turkey. The demog...