Life abounds with genetic variations writ in sequences that are often only a few hundred nucleotides long. Rapid detection of these variations for identification of genetic diseases, pathogens and organisms has become the mainstay of molecular science and medicine. This report describes a new, highly informative closed-tube polymerase chain reaction (PCR) strategy for analysis of both known and...

In recent years, the electrical consumption of data centers has increased considerably leading to a rise in the expenditure bill and in greenhouse gas emissions. Several existing on/off algorithms reduce energy consumption in data centers or Clouds by turning off unused (idle) machines. However, the turning off/on of servers consumes a certain amount of energy and also induces the wear and tear...

The involvement of N-glycans in the folding of influenza virus hemagglutinin (HA) was analyzed in two CHO-derived glycosylation mutants exhibiting a thermosensitive defect for secretion of human placental alkaline phosphatase. Truncated Man(5)GlcNAc(2)oligosaccharides with one or three glucose residues are attached to proteins of the MadIA214 and B3F7AP2-1 mutant cells, respectively. Newly synt...

Even if A Stir of Echoes (1958) has often been overshadowed by Richard Matheson’s best-known novels I Am Legend (1954) and The Shrinking Man (1956), it should be given the credit it deserves as a novel that functions both as a reflection as well as a source of intertextuality. A Stir of Echoes is rooted in the tradition of the ghost story and the American gothic, but above all, it comprises mot...

fiction has a special position because of its charisma and special charm and is considered as an important literary device; the most important task of story is to promote the moral and spiritual virtues of characters and to fight evil and injustices. therefore, dedicated novelist should try not only to entertain the reader but also to be aware of his ultimate goal; which is to teach and to info...