نتایج جستجو برای: thiopurine s methyl transferase
تعداد نتایج: 821797 فیلتر نتایج به سال:
background: the glutathione s-transferase (gst) family of metabolising enzymes plays an important role in the detoxification of mutagens and carcinogens. the expression of many of these cancer susceptibility enzymes is genetically polymorphic. an increased frequency of gst-null genotypes has been associated with several malignancies. objective: to investigate the rate of gstt1 and gstm1 null ge...
no association of gstm1 null polymorphism with endometriosis in women from central and southern iran
background: endometriosis is one of the most common gynecologic disorders. it is a complex trait and both genetic and environmental factors have been implicated in its pathogenesis. there is growing evidence indicating that exposure to environmental contaminants is a risk factor for endometriosis. glutathione-s-transferase m1 (gstm1) is one of the genes involved in detoxification of endogenous ...
BACKGROUND/AIMS The long-term clinical outcomes of patients with bio-naive ulcerative colitis (UC) who maintain remission with thiopurine are unclear. The aim of this study was to assess the long-term efficacy and safety of maintenance treatment with thiopurine in UC patients. METHODS This was a retrospective observational cohort analysis conducted at a single center. Between December 1998 an...
The relationship between reduced glutathione (GSH) level and glutathione S-transferase (GST) activity in erythrocytes was examined, using sheep erythrocytes, which have varying GSH concentrations, and dog erythrocytes with an inherited high concentration of GSH. There was a positive correlation (r = 0.529, p < 0.001) between the GSH level and GST activity in sheep erythrocytes. In dog erythrocy...
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