The localization and chemical determination of acetylcholin esterase in the frog sympathetic and dorsal root ganglia were studied by a combination of the methods of electron microscopy, histochemistry, and microgasometric analysis with the magnetic diver. The Koelle-Friedenwald copper thiocholine histochemical method was modified by eliminating the sulfide conversion and by treatment of the tis...

Cholinergic as well as monoaminergic neurotransmission seems to be involved in the etiology of affective disorders. Chronic treatment with imipramine, a classical antidepressant drug, induces adaptive changes in monoaminergic neurotransmission. In order to identify possible changes in cholinergic neurotransmission we measured total, membrane-bound and soluble acetylcholinesterase (Achase) activ...

S-Succinylglutathione hydrolase, a new highly specific glutathione thiol esterase, has been purified from human liver. The preparation obtained is homogeneous according to disc electrophoretic and ultracentrifugal criteria and catalyzes the hydrolysis of 3000 pmol of Ssuccinylglutathione/min/mg of protein at 25°C. The enzyme has no activity toward nine other glutathione thiol esters tested or s...

driver drowsiness has been one of the main causes of on-road crashes which can lead to death, physical injuries and impose significant costs on the societies. the development of non-intrusive methods to be able to detect driver drowsiness in the early stages of drowsiness is great of importance. this is an educational review and its purpose is to provide recent achievements about non-intrusive ...

background and aims: rotaviruses are one of the main causative agents of acute viral gastroenteritis in both young human and animals. several methods have been used for diagnosis of rotavirus infection. most of these methods are not easily available in iran. methods: in our study attempt was made to develop a method which could replace the commercially imported kit. rota virus was purified and ...

This work studies the impact of electrostatic interaction between analyte molecules and silver nanoparticles (Ag NPs) on intensity surface-enhanced Raman scattering (SERS). For this, we fabricated nanostructured plasmonic films by immobilization Ag NPs glass plates functionalized them a set differently charged hydrophilic thiols (sodium 2-mercaptoethyl sulfonate, mercaptopropionic acid, 2-merca...

leishmaniasis is a common parasitic disease in tropical and subtropical areas of the world. police personnel deployed in the suburbs and rural areas are the most often exposed to the potential risk of cutaneous leishmaniasis. furthermore, since the same police personnel are sent on duty to other places, their migrations can also play a considerable role in the transmission of this disease to th...

how to cite this article: karimzadeh p, jafari n, alai mr, jabbehdari s, ahmad abadi f, nejadbiglari h. homocystinuria: diagnosis and neuroimaging findings - of iranian pediatric patients. iran j child neurol. 2015 winter;9(1):94-98. abstract objective homocystinuria is a neurometabolic diseases characterized by symptoms include neurodevelopmental delay, lens dislocation, long limbs and thrombo...

calcineurin (can) is a ca2+/calmodulin (ca2+/cam)-dependent serine/threonine protein phosphatase expressed in most mammalian tissues but found at higher concentration in brain. in the last decade there have been a steadily increasing number of studies identifying neuronal can as a primary suspect in neuronal vulnerability, synapse loss, dendritic atrophy, synaptic dysfunction and neuroinflammat...