Simple gel formulations may be applied to enhance the systemic and local exposure of potential compounds. The aim of this thesis is the development and characterization of controlled release formulations based on thermoreversible poloxamer gels, which are suitable for novel drug delivery applications. In particular co-solvents (DMSO, ethanol), mucoadhesive polymers (chitosan, alginate) and salt...

The dimensional stability and rheological properties of a series of comb-like copolymers of N-isopropyl acrylamide (NIPAAm) and methoxy poly(ethylene glycol) methacrylate (mPEGMA), poly(NIPAAm-co-mPEGMA), with varying poly(ethylene glycol) (PEG) graft densities and molecular weights were studied. The thermoresponsive character of the copolymer solutions was investigated by kinetic and equilibri...

Silica aerogels prepared by the sol-gel process are often used as solid desiccants in enthalpy wheels for dehumidifying ventilation air in air-conditioning systems. These hygroscopic materials have good moisture adsorption and desorption characteristics due to their porous structure. The current study is focused on the evaluation of the mass diffusivity of solid silica aerogels and silica aerog...

Organic aerogels were synthesized by sol–gel polymerization of resorcinol (R) with formaldehyde (F) catalyzed by sodium carbonate (C) followed by vacuum drying. The influence of the resorcinol/sodium carbonate ratio (R/C) on the porous structure of the resultant aerogels was investigated. The nitrogen adsorption–desorption measurements show that the aerogels possess a well developed porous stru...

This paper reports on the thermodynamics through mapping out temperature–concentration phase diagrams and molecular structure morphology of binary organogels prepared with trisamide triarylamine (TATA) in tetrachloroethane their ternary thermoreversible hybrid gels formed polyvinyl chloride (PVC). For low PVC contents, TATA organogel moiety behaves as systems, while for higher thermal behavior ...

Silica aerogels are nanoporous ultralight new materials with extraordinary material properties. In this study, the mechanical properties of silica aerogels, e.g. Young’s modulus, Poisson’s ratio and constitutive relation, are investigated using Molecular Dynamics (MD) simulations and theoretical analysis. In molecular dynamics simulations, an improved process of negative pressure rupturing meth...

Carbon-based aerogels, composed of interconnected threedimensional (3D) networks, have attracted intensive attention because of their unique physical properties, such as low density, high electrical conductivity, porosity, and specific surface area. As a result, carbon-based aerogels are promising materials used as catalyst supports, artificial muscles, electrodes for supercapacitors, absorbent...