We propose a scenario for the prebiotic co-evolution of RNA and of fast folding proteins with large entropy gaps as observed today. We show from very general principles that the folding and unfolding of the proteins synthesized by RNA can function as a heat pump. Rock surfaces can facilitate the folding of amino acid chains having polar and hydrophobic residues, with an accompanying heat loss t...

Physical gels are characterized by dynamic cross-links that are constantly created and broken, changing its state between solid and liquid under influence of environmental factors. This restructuring ability of physical gels makes them an important class of materials with many applications, such as in drug delivery. In this article, we present a thermodynamic model for physical gels that consid...

A Bayesian approach to model comparison based on the integrated or marginal likelihood is considered, and applications to linear regression models and nonlinear ordinary differential equation (ODE) models are used as the setting in which to elucidate and further develop existing statistical methodology. The focus is on two methods of marginal likelihood estimation. First, a statistical failure ...

In this work, we have studied the solvent effects on values of Gibbs free energy, enthalpy. entropy and dipolemoment in spread of solvents around anticancer thug of temreolomide that is an alighting agent. For thispurpose, the quantum mechanic calculations bawd on Hanrertnick theory at the STO-36/3-2Ith levels havebeen done. Moreover, we have compared resulted thermodynamic values in gas phase ...

in this paper, the application of neural networks for simulation and optimization of the cogeneration systems has been presented. cgam problem, a benchmark in cogeneration systems, is chosen as a casestudy. thermodynamic model includes precise modeling of the whole plant. for simulation of the steadysate behavior, the static neural network is applied. then using dynamic neural network, plant is...

a numerical framework has been proposed to model the interacting effects of mixture non-ideality and mass transfer on hydrodynamics of a multiphase system using cfd methods.mass transfer during condensation and vaporization is modeled by chemical potential at the liquid-vapor interface. species mass transfers are related to the diffusion at the interface which in turn is related to the concentr...

The modified square well Potential is combined with perturbed-hard-trimer-chain (PHTC) EOS to predict the solubility parameter of several fluids including alkanes, refrigerants and molten polymers. The performance of the proposed model has been evaluated by predicting the solubility parameter of 12 hydrocarbons,3 refrigerants, and 12 polymers. From the 263 data points for hydrocarbons and refri...

This paper gives a general view of a recently developed thermodynamic model of the thermoelastic rnartensitic transformation. Unlike existing empirical, mathematical or thermodynamic models, this generalised thermodynamic model can be used to understand and describe quantitatively the overall thermomechanical behaviour of polycrystalline shape memory alloys. Important points of difference betwe...