The principle of Per-Survivor Processing (PSP) provides a general framework for the approximation of likelihood-based data detection (search) algorithms whenever the presence of unknown quantities prevents the precise use of the classical Viterbi Algorithm (VA). The PSP concept is based on the realization that decision-directed estimation of the relevant unknown parameters should be embedded in...

INTRODUCTION This case report describes a human survivor of Balamuthia mandrillaris infection. This is a free-living amoeba that can cause infection with the devastating consequence of near universally fatal encephalitis. We report this case to demonstrate the possibility of recovery. CASE PRESENTATION A 26-year-old Hispanic male, a landscape gardener, presented to the hospital in March 2010 ...

Gabriel Chodick, [email protected], NCI Chuck Sklar, [email protected], MSKCC Wendy Leisenring, [email protected], F. Hutchinson Cancer Res Center Ann Mertens, [email protected], U Minn Marilyn Stovall, [email protected], MDACC Susan Smith, [email protected], MDACC Rita Weathers, [email protected], MDACC Les Robison, [email protected], St. Jude Ruth Kleinerman, klei...

In survival or reliability studies, it is common to have truncated data due to the limited time span of the study or dropouts of the subjects for various reasons. The estimation of survivor function under left truncation was first discussed by Kaplan and Meier by extending the well known productlimit estimator of the survivor function. The focus of this paper is on the nonparametric estimation ...

Bacteria owe much of their evolutionary success to the development of mechanisms that enable survival under harsh conditions; despite their importance, however, we have only recently begun to understand these survival strategies. Several of these mechanisms have been shown to target ribosomes, robustly blocking their ability to translate mRNAs into proteins and preserving their integrity in res...

Unlike patients in a randomized, clinical trial, patients in an observational study choose if and when to begin treatment. Patients who live longer have more opportunities to select treatment; those who die earlier may be untreated by default. These facts are the essence of an often overlooked bias, termed "survivor treatment selection bias," which can erroneously lead to the conclusion that an...

Addressing gaps in the research, the current study assesses the impact of a community-based child sexual abuse prevention program on known survivor knowledge/skills, disclosures, and subjective experience. Methodologically, novel measures of program fidelity and implementation cost are applied. A pre- posttest wait-list control design was utilized with intervention (n = 10) and comparison group...

Breast cancer survivors must manage chronic side effects of original treatment. To manage these symptoms, communication must include both biomedical and contextual lifestyle factors. Sixty breast cancer survivors and 6 providers were recruited to test a conceptual model developed from uncertainty in illness theory and the dimensions of a patient-centered relationship. Visits were audio-taped, t...

Testimonies of Holocaust survivors have had an essential influence on public engagement with the Shoah in recent decades. Given this importance, imminent end “era witness” has sparked fears that history could soon be forgotten. The past decades therefore seen unprecedented efforts to record testimonies order safeguard immediacy their accounts. In essay, I trace how different temporal entangleme...