Natural resource-based projects represent an important sector in Canada’s economy, where the energy, mining, and forestry industries accounted for 17% of gross domestic product 2018 (Natural Resources Canada, 2019). Many are located on or near Indigenous lands, disproportionately impacting peoples (Gibson et al., 2017). The negative environmental impacts well documented (Koutouki 2018; Westman ...

CRISPR-Cas loci encode for an adaptive immune system in prokaryotes that provides defense against viruses (1) and plasmids (2) that infect these organisms. CRISPR loci contain a series of repetitive sequences intercalated with short sequences derived from invading viruses and plasmids (3–5). These short sequences, called spacers, are acquired from the invader upon infection during an “immunizat...