BACKGROUND Studies investigating the association of cadmium and sex steroid hormones in men have been inconsistent, but previous studies were relatively small. METHODS In a nationally representative sample of 1,262 men participating in the morning examination session of phase I (1998-1991) of the third National Health and Nutrition Examination Survey, creatinine corrected urinary cadmium and ...

the effects of steroid hormones, glucagon and insulin on rat liver phosphatidate phosphohydrolase (pap) activity were studied both in vitro and in vivo. incubation of rat hepatocytes with each hormone showed that dehydroepiandrosterone (dhea), progesterone and testosterone increase pap activity by 44.6, 37 and 36.9%, respectively. estradiol, however, decreased enzyme activity by 13.6% under the...

Tumors in female Swiss Millerton mouse skin were initiated with 25 pg 7,12-dimethylbenz(a)anthracene and, 2 weeks later, were promoted 3 times/week with 0.2 ml of 0.5% croton oil. Four steroid hormones in 0.2 ml of acetone were applied percutaneously at 6 and 30 jug 5 times/week. A fifth steroid was applied at the 30-^g dose. Tumor inhibition by the hormones was dose dependent in the order dexa...

The simultaneous quantitation of multiple steroid hormones in real time is of great importance in medical diagnosis. In this study, a portable hormone biosensor based on duplex molecular recognition coupled with a signal-amplified substrate was successfully developed for the simultaneous visualization and quantitation of multiple steroid hormones. Aptamer-functionalized upconversion nanoparticl...

You have accessJournal of UrologyProstate Cancer: Basic Research & Pathophysiology II (PD44)1 Sep 2021PD44-02 PHARMACOGENOMIC DETERMINANTS OF SERUM STEROID HORMONE RESPONSES TO ABIRATERONE OR ENZALUTAMIDE AND HSD3B1 GENE MUTATION IN CRPC PATIENTS Hosam Serag, Emilia Chen, Hans Adomat, Daniel Khalaf, Alexander Wyatt, and Martin Gleave SeragHosam Serag More articles by this author , ChenEmilia Ch...