introduction: vaccination with the major surface antigen of hepatitis b virus (hbsag) induces anti-hbs antibody production and level of 10 iu/l is considered protective. it has been shown that the level of anti-hbs antibody does wane after vaccination. the aim of this study was to evaluate the persistence of anti-hbs antibodies in healthy iranian children 10 years after primary vaccination. met...

comparative study on toxoplasma serology among hiv positive and hiv negative illicit drug users in ahvaz, iran

bakcground: the aim of itp treatment is to prevent intracranial hemorrhage and increase the platelet count rapidly. this study was conducted with the objective of comparing the efficacy of anti-d immunoglobulin (ig) with dexamethasone in treating childhood itp. materials and methods: in this randomized prospective control trial, 20 itp patients (platelet count< 20,000/µl) younger than 16 were s...

background: erythropoietin (epo) was first known as a factor for red blood cell proliferation and differentiation. new studies show the effects of epo on immune system. objective: in this study, the effects of pretreatment with recombinant human erythropoietin (rhuepo) on the anti-human leukocyte antibody (anti-hla) titer were determined. methods: three groups of rats were sensitized with human...

background: different methods have been used for characterization of leishmania promastigotes. monoclonal antibodies are useful in characterization of   leishmania spp . both amastogotes and promastigotes. objective: comparing the characterization of   leishmania spp. promastigotes with immunoperoxidase test (avidin-biotin) techniques and an indirect immunofluorescent assay (ifa).   methods: ap...

background and objectives: tetanus and diphtheria are vaccine-preventable, infectious diseases with significant morbidity and mortality. immunization by the diphtheria and tetanus toxoid (dt) has been applied in iran for almost 50 years. however, there are very few data about the rate of immunity to these diseases in the adult population. the humoral immunity to tetanus and diphtheria among blo...

purpose: to evaluate the vascular occlusion in coats’ disease   methods: in this non-comparative case series, 13 consecutive patients with coats’ disease from january 2011 to september 2011 were included. the hypercoagulability states were evaluated in these patients.   results: the mean age of the patients in this series was 15.4 years. all but one patient had high anti-cytomegalovirus antibod...

conclusions the r-b-flagellin carried antigenic epitopes just like the native flagellin, while the polyclonal antibody raised against it exhibited functional activity. results the polyclonal antibodies raised against this r-b-flagellin inhibited the motility of the homologous pao1 strain of p. aeruginosa, which significantly decreased the invasion of the pao1 strain into the a549 cells and also...

background: allergens are mostly composed of glycoprotein structures. it is believed that glycan-specific antibodies may lead to false-positive reactions in immunoassays. in this study we investigated the glycosylation state of grape allergens as well as the presence of antibodies to cross-reactive carbohydrate determinants (anti-ccds) in sera from grape-sensitive individuals. methods: grape ex...