Tetanus is vaccine preventable disease still measure cause of fatality in developing country like India. We review the history, epidemiology, pathophysiology, clinical presentation, diagnosis and management of tetanus along with series of 3 cases reported in our district hospital in last 2 years. Among 3 cases, two were of otogenic tetanus in children with incomplete or unknown immunization sta...

A case report of cephalic tetanus in a 2-year-old girl who was not immunized against tetanus following suppurative otitis media (SOM) is presented. This case is reported because of the rarity of cephalic tetanus associated with high mortality, to highlight the risk of cephalic tetanus as sequelae of SOM and the need for proper aural care and prompt treatment of SOM. Primary immunization of all ...

Tetanus is a disease caused by the toxin produced by Clostridium tetani. The clostridium tetanus bacterium is ubiquitous, and as such, C tetani infection can be acquired through surgery, intravenous drug abuse, the neonate’s umbilicus, bites, burns, body piercing, puncture wounds, and ear infections. In short, this organism can enter through any break in the integrity of the body. As a result o...

Abstract Background Coronavirus Disease 2019 (COVID-19) is a viral pandemic disease that may induce severe pneumonia in humans. In this paper, we investigated the putative implication of 12 vaccines, including BCG, OPV and MMR protection against COVID-19. Sequences main antigenic proteins vaccines SARS-CoV-2 were compared to identify similar patterns. The immunogenic effect identified segments ...

Botulinum neurotoxins and tetanus are the strongest known toxins that cause neuroparalytic syndromes in botulism tetanus. This review aimed to systematize scientific data on structures mechanism of actions botulinum neurotoxins. proteins containing functional domains responsible for receptor binding, transmembrane translocation, proteolytic cleavage required exocytosis synaptic vesicles release...

A - 7 month old female etawa belongs to Mr. Joko It shows that has problems of difficulties opening it's mouth and soundless for three days. The physical check is carried out through palpalis from goat's nails, legs, in the area. result checks found goat could not open got pain while touching it. In area scars. indicates spesial tetanus., this was diagnosed with tetanus, where characteristic sy...

BACKGROUND Neonatal tetanus remains an important and preventable cause of neonatal mortality globally. Large reductions in neonatal tetanus deaths have been reported following major increases in the coverage of tetanus toxoid immunization, yet the level of evidence for the mortality effect of tetanus toxoid immunization is surprisingly weak with only two trials considered in a Cochrane review. ...

BACKGROUND Tétanos Quick Stick® (TQS) is a test for tetanus immunity screening for wounded patients in emergency departments (EDs), but represents additional costs compared with a medical interview on vaccination history. The study objective was to assess the effectiveness and cost of the TQS in French EDs. METHODS We performed a model-based analysis that simulates screening of tetanus immuni...

BACKGROUND Neonatal tetanus continues to occur in many resource-limited settings but there are few data regarding long-term neurological outcome from the disease, especially in settings with critical care facilities. METHODS We assessed long-term outcome following neonatal tetanus in infants treated in a pediatric intensive care unit in southern Vietnam. Neurological and neurodevelopmental te...

the incidence of tetanus among wounded patients in greater isfahan in 5 years with their mortality was discussed, careful review of the literature. with consideration of commendations of the committee on trauma of the american college of surgeons, the german association for surgery and the swedish college .of surgeons about type of prophylactic measurement discussed and finally the basic trends...