A rare case of a seminoma developing in an atrophic testis is described and the role of testicular atrophy in tumorigenesis is discussed. S. Ali Khan, Chief of Urology, Veterans Administration Medical Center, Northport, NY 11768 (USA) Introduction Testicular tumors are rare, accounting for less than 2% of all male malignancies. Testicular tumors occurring in atrophic testes are seen even less f...

A rare case of a seminoma developing in an atrophic testis is described and the role of testicular atrophy in tumorigenesis is discussed. S. Ali Khan, Chief of Urology, Veterans Administration Medical Center, Northport, NY 11768 (USA) Introduction Testicular tumors are rare, accounting for less than 2% of all male malignancies. Testicular tumors occurring in atrophic testes are seen even less f...

Malignant mesotheliomas of the testis arise from the tunica vaginalis, formed from the evagination of the abdominal peritoneum into the scrotum. It is an extremely rare tumor representing 0.3% to 5% of all malignant mesotheliomas. We presented an interesting case of 68-year-old male with swelling and slightly painful in the right scrotum. Histologically, the lesion were composed of small tubula...

Biotransformation of steroid hormones by a spontaneous interstitial cell tumor originating from a BALB/cJ mouse has been studied in vitro. Tumor tissue grown in a female host converted estrone predominantly to estradiol-17~. The same tissue transformed estradiol-17/~ to estrone to a considerably lesser extent. Incubation of the tumor tissue with androstenedione yielded testosterone as the princ...

Sarcoidosis is an idiopathic, multisystem disease that rarely involves the genitourinary tract. Here we present an unusual case of testicular sarcoidosis with extensive lymphadenopathy that mimicked a metastatic testicular tumor. A 27-year-old male presented with a palpable right testicular mass accompanied by multiple palpable inguinal lymph nodes. The scrotal ultrasound showed a hypoechoic le...

Adrenogenital Syndrome, more properly defined as Congenital Adrenal Hyperplasia (CAH), is related to the enzyme 21-beta-hydroxylase deficiency, with impaired glucocorticoids and aldosterone syntheses and increased ACTH synthesis. This report describes a case of a monorchid patient suffering from Adrenogenital Syndrome and Leydig cell tumor of his testis. A right orchidectomy with implantation o...

Supernumerary testis, also known as polyorchidism, is a condition characterized by the presence of more than two testes. Another condition of the testes is seminoma, a common cause of testicular germ cell tumor. A 35-year-old male was transferred to our hospital with a diagnosis of abdominal mass causing abdominal pain. On physical exam, he had a palpable undescended left testicle in the left i...

UNLABELLED A 19-year-old patient was diagnosed with a neuroendocrine tumor (NET) of the testis and suffered from testicular pain and swelling after orchiectomy. After a comprehensive diagnosis, this tumor was shown to be a primary, metastasizing NET of the testis. Primary NETs of the testis are very rare; in the literature, only approximately 60 patients of all ages are mentioned. Less than 20%...

Cancer-testis antigens are tumor antigens that their expression is almost limited to male germ cells in the testis. Some of cancer-testis antigens are also expressed in the ovary and in trophoblasts. Recently their expression has been seen in different types of tumors. Many pathophysiologic studies suggest that a blood-testis barrier exists in the testis. Because spermatogenesis begins at puber...