the importance of extra cellular matrix (ecm) in development and function of different cells has been reported but little is known about its role in human endometrial epithelial cells. the aim of the present study was to examine effects of artificial ecm (matrigel) and progesterone on the function and morphology of human endometrial epithelial cells in vitro. methods: endometrial samples were r...

Background: Ceftriaxone is an antibiotic used for treating respiratory,skin,bone and kidney infections. Our purpose was investigating effect of ceftriaxone on testicular tissue. Materials and Methods: 40 mice with 6 weeks old were used in this study. The mice randomly were divided into 2 groups, control- sham and test groups. The test group was subdivided to IP1 and IP2 which received Ceftriaxo...

Dynamic and reciprocal epithelial-mesenchymal interactions are critical for the normal morphogenesis and maintenance of epithelia. Epimorphin has been identified as a unique molecule expressed by mesenchymal cells and myofibroblasts and has putative morphogenetic effects in multiple epithelial tissues, including intestine, skin, mammary gland, lung, gallbladder, and liver. To define the in vivo...

Abstract Diabetes mellitus (DM) is one of the greatest public health threats in modern societies. Although during a few years it was suggested that DM had no significant effect in male reproductive function, this view has been challenged in recent years. From a clinical perspective, the evaluation of semen parameters, as well as spermatozoa deoxyribonucleic acid (DNA) integrity, are often st...

Cytological changes of the epithelial cells according to the developmenatal phases of the seminal vesicle related to the spermatogenic stages in the testicular lobules during spermagenesis in male Neptunea (Barbitonia) cumingii (Gastropoda: Buccinidae) were investigated monthly by electron microscopical and histological observations. N. (B) cumingii is dioecious, and an internal fertilization s...

Background: Endometriosis is the presence of a functional endometrial tissue outside the uterine cavity and defines as cancer like model. Noscapine is a safe cough suppressant which has been introduced as cancer suppressor. The aim of this study was to investigate the in vitro effect of noscapine on human endometriotic epithelial cells. Materials and Methods: Human endometriotic biopsies (n=7) ...