Objective. Plasmid-mediated quinolone resistance (PMQR) plays an important role in the development of clinical resistance to quinolone. The aim of this study was to investigate PMQR determinants among extended-spectrum β-lactamases- (ESBL-) producing Klebsiella pneumoniae recovered from patients with nosocomial urinary tract infection (UTI). Methods. A total of 247 ESBL-producing K. pneumoniae ...

UNLABELLED The aim of this study was to determine the prevalence of ESBL-producing Escherichia coli and Klebsiella pneumoniae as well as genes encoding ESBLs. MATERIAL AND METHODS A total of 1207 non-repeat isolates of E. coli and K. pneumoniae were obtained from urine, tracheal aspirate, wound swab and blood from patients hospitalized at the University Clinics in Skopje. ESBL set and E-test ...

BACKGROUND The spread of Extended-Spectrum beta (β)-Lactamases (ESBL)-producing Enterobacteriaceae has become a serious global problem. ESBL-producing Enterobacteriaceae vary based on differences in antibiotic use, nature of patients and hospital settings. This study was aimed at determining ESBL and antibiogram in Enterobacteriaceae isolates from clinical and drinking water sources in Bahir Da...

Objective(s) This study was carried out to evaluate the existence of the TEM, SHV and PER ESBL genes in ESBL producing strains of Pseudomonas aeruginosa isolated from burnt patients at Shafa-hospital, Kerman, Iran. Materials and Methods A total of 120 strains of P. aeruginosa were isolated from 245 patients in burn unit of Shafa-hospital during January 2006 to December 2007. MIC of antibioti...

In this study, the presence of extended spectrum beta lactamase (ESBL) producing organisms in abattoirs, a non-hospital community was investigated. The presence of ESBL-producing phenotypes was confirmed by the Double Disc Synergy Test (DDST). Out of the 99 isolates screened for ESBL, 28 (28.3%) were confirmed positive. The positive isolates were characterised by using Matrix-Assisted Laser Des...

PURPOSE This study was undertaken to analyze the extended spectrum of β lactamase (ESBL), metallo β lactamase (MBL) & AmpC production in Pseudomonas aeruginosa in various clinical samples. MATERIALS & METHODS One hundred four non repetitive clinical specimens were inoculated onto nutrient agar, blood agar and incubated at 37(o)C overnight. The colonies were tested for oxidase test and other b...

Objective: Bacteria develop resistance to many antibiotics by using different mechanisms. The of bacteria secreting extended-spectrum beta-lactamases limits our treatment options. In this study, we investigated the in vitro efficacies non-beta-lactam Escherichia coli (E. coli) and Klebsiella spp. strains. Material Method: presence ESBL 97 ESBL-negative (61 E. coli, 36 spp.) 54 ESBL-positive (33...

extended-spectrum β-lactamase (esbl)-producing enterobacteria has become a considerable global concern because of their potential dissemination in humans, in domestic animals, wildlife and the environment. the present study aimed to explore the esbl producing  enterobacteria in aquatic sources of bangladesh as the water may be the potential source of dissemination of this alarming antimicrobial...

BACKGROUND AND OBJECTIVES Various phenotypic methods are recommended in the routine practice to detect the ESBL production in gram negative bacilli. Among them, the Double Disc Synergy Test (DDST) which uses the third generation cephalosporins (3GC), is a simple and a reliable method. But the coexistence of AmpC may give false negative results. In such cases, the ESBL detection can be improved ...

Cefpodoxime is one of five antimicrobial agents recommended by the National Committee for Clinical Laboratory Standards for screening isolates of Klebsiella spp. and Escherichia coli for extended-spectrum beta-lactamase (ESBL) production. In a prior study, we noted that among 131 E. coli isolates for which the MIC of at least one extended-spectrum cephalosporin (ESC) or aztreonam was > or =2 mi...