[reaction: see text] Treatment of hydroxy-substituted silyl epoxides with Grignard reagents induces a 1,2-carbon shift to reveal alpha-silyl aldehydes, which are trapped by highly diastereoselective addition reactions of the Grignard reagent. The starting epoxides are readily accessible from propargylic alcohols by regio- and diastereoselective hydrosilylation and epoxidation reactions. In addi...

Spain has made major investments in tertiaryeducation...  Between 1995 and 2003, Spain has made major investments in tertiary education. Expenditure per student has increased by 43% which is the third highest increase in the OECD countries (OECD average of 6%). As the number of students in tertiary education has also increased by 11% during this period, overall expenditure has increased by 58%...

The efficiency of direct conversion of tertiary alcohols bearing a β-hydrogen atom to vicinal halohydrins-chlorohydrins and bromohydrins-under green reaction conditions was tested preliminarily on model tertiary benzyl alcohols. Tertiary alcohols were successfully directly halogenated to vicinal halohydrins with N-halosuccinimide in aqueous media. The efficiency of the reaction in water was sig...

BACKGROUND A patient left without being seen is a well-recognized indicator of Emergency Department overcrowding. The aim of this study was to define the characteristics of LWBS patients, their rates and associated factors from a tertiary care hospital of Pakistan. METHODS A retrospective patient record review was undertaken. All patients presenting to the Aga Khan University Hospital, Karach...

compares well with MGIT in terms of recovery rate and detection time, and detects mycobacterial growth much faster than the LJ medium. The Bio FM vial is about 30% cheaper than the MGIT vial and does not need any capital investment. Thus, it can be used in settings where cost and/ or infrastructural limitations prohibit usage of fully automated systems. Also, its usage will facilitate reporting...

A giant magnetocurrent (>100%) is observed in the electrochemical system based on tertiary amines at room temperature. This giant magnetocurrent is ascribed to spin-dependent deprotonation during the oxidation of tertiary amines. This presents a new approach of using spin-dependent deprotonation to generate giant magnetocurrent in electrochemical reactions.

The Douglas Inquiry has clearly illustrated systematic deficiencies in the delivery and regulation of Obstetric and Gynaecological services. Such problems are not unique to the KEMH. Irrespective of the specialty, seven million dollars of careful analysis at any Australian tertiary hospital would have yielded the same conclusions. What lies at the core of the problem are grossly deficient indus...