lamotrigine is used in the treatment of cns disorders, particularly epilepsy; pain; oedema; multiple sclerosis and psychiatric indications including bipolar disorder. lamotrigine belongs to biopharmaceutical classification systems, bcs class ii (low solubility & high permeability). in addition, it requires immediate therapeutic action hence the main objective of this study is to improve the sol...

Protonic conductors of BaZr0.5Ce0.3Ln0.2O3-δ (BZCLn532, Ln=Y, Sm, Gd, Dy) were successfully synthesized by using a cost-effective solid state reactive sintering (SSRS) method with 1 wt.% NiO as a sintering aid. The pellets of the BZCLn532 were obtained at sintering temperatures between 1300 1600 °C. The results show that the morphologies and the final relative densities of the obtained BZCLn532...

In the last few years nanostructure ZnO is being intensively investigated from the growth control, structural and physical characterization, to device performance. There are now increasing interests in a wide range of ZnO-based ternary compound nanostructures offering even larger possibilities. These compounds can be useful as multi-color light-emitting device, sensors, transparent electrodes, ...

Solid-state compatibility and melting relationships in the subsystem Al2O3–MgAl2O4–CaAl4O7 were studied by firing and quenching selected samples located in the isopletal section (CaOzMgO)–Al2O3. The samples then were examined using X-ray diffractomtery, optical microscopy, and scanning and transmission electron microscopies with wavelengthand energy-dispersive spectroscopies, respectively. The ...

The isoplethal sections CaAl2O4–MgO and CaAl4O7–MgO of the Al2O3–MgO–CaO ternary system have been experimentally established at 1 bar total pressure and air of normal humidity. The sections obtained provide new data and information that are in disagreement with thermodynamic evaluations and optimizations of the Al2O3–MgO–CaO ternary system published to date. These differences arise mainly from ...

The fluorolytic sol-gel synthesis for binary metal fluorides (AlF₃, CaF₂, MgF₂) has been extended to ternary and quaternary alkaline earth metal fluorides (CaAlF₅, Ca₂AlF₇, LiMgAlF₆). The formation and crystallization of nanoscopic ternary CaAlF₅ and Ca₂AlF₇ sols in ethanol were studied by 19F liquid and solid state NMR (nuclear magnetic resonance) spectroscopy, as well as transmission electron...

INTRODUCTION Many drugs show bioavailability problems due to their low water solubility, slow dissolution rate, and instability in the gastrointestinal tract. Nimesulide is a non-steroidal anti-inflammatory, analgesic and antipyretic agent, chemically is N-(4 nitro-2-phenoxyphenyl) methane sulfonamide. It is poorly soluble in water and irregularly absorbed by gastrointestinal tract. Among the v...

Studying waste discharge concentration across a convergent/divergent channel is essential in environmental-related applications. Successful environmental administration must understand the behavior and of contaminants released into these channels. Analyzing concentrations aids determining efficacy treatment techniques regulatory controls lowering pollutant scales. Because this, current analysis...