objective: tendon never returns to its complete biological and mechanical properties after repair. bone marrow and, recently, adipose tissue have been used as sources of mesenchymal stem cells which have been proven to enhance tendon healing. in the present study, we compared the effects of allotransplantation of bone marrow derived mesenchymal stromal cells (bmscs) and adipose derived stromal ...

introduction: traumatic ruptures of the biceps tendon are rare, but serious, and usually involve the long head of the proximal insertion. rupture of the distal tendon account for only 3% of all biceps tendon ruptures. a history of tendonitis, overuse, or anabolic steroid abuse may predispose tendons to rupture. surgical repair, followed by a comprehensive rehabilitation program, was indicated t...

INTRODUCTION Rotator cuff tears of the shoulder are a common cause of pain and disability and surgical repair of these injuries is plagued with recurrent tear rates ranging from 20-70% [1]. The time from onset of injury to time of surgical repair is one important factor in repair outcome [2]. Animal models have recently been developed to address hypotheses related to rotator cuff tendon to bone...

The contribution of inflammation to the pathogenesis of tendinopathy and high prevalence of re-injury is not well established, although recent evidence suggests involvement of prostaglandins. We investigated the roles of prostaglandins and inflammation-resolving mediators in naturally occurring equine tendon injury with disease stage and age. Levels of prostaglandins E(2) (PGE(2)), F(2α) (PGF(2...

The aim of the current study was to investigate the effect of inhibition of nitric oxide (NO) production after injury on inflammatory cell accumulation and fibrosis around digital flexor tendon and synovium. A standard crush injury was applied to the flexor tendons of the middle digit of the hindpaw and the overlying muscle and synovium of female Wistar rats. Thirty animals received an intraper...

BACKGROUND Complete triceps tendon ruptures are relatively rare in the general population but slightly more prevalent in professional football. One prior study found 11 complete ruptures over a 6-season period. HYPOTHESIS Triceps ruptures occur more commonly in football linemen due to forced elbow flexion during an eccentric contraction and may occur more commonly with the increasing size and...

Bone-tendon junction (BTJ) overuse injuries are common athletic and occupational problems. BTJ injuries may sometimes be caused by resuming training too early after injury. To study the effects of post-injury resuming training within 48 hours on the acute injury healing process, as it is often the case for athletes. Twelve mature female rabbits were assigned to one of the following groups: acut...

Quadriceps tendon rupture is an uncommon injury that usually occurs in middle-aged and elderly men with a history of chronic illnesses. We report the case of a 17-year-old healthy adolescent male baseball player who sustained this injury as a result of sudden deceleration in his left knee. He initially reported to the emergency department and then presented to our practice, where he was diagnos...

The most frequently injured tendons and ligaments in the horse are those on the palmar or plantar aspect of the distal limb. For this reason, this series of presentations will focus on these injuries. Diagnosis of strain-induced tendon injuries of the equine distal limb are based on history (usually a preceding period of exercise) and the development of the signs of inflammation (pain, heat, sw...

Changes in the concentration of the major glycosaminoglycan compounds were measured during healing of severed Achilles tendons in rabbits. Using zone electrophoresis for separation, and densitometry for quantitation of these compounds, their concentrations could be measured in each of several portions of the tendon and its associated muscle. Immediately after injury, the concentration of hyalur...