Baskies M, Tuckman DV, Paksima N. Management of flexor tendon injuries following surgical repair. Bull NYU Hosp Jt Dis. 2008;66(1):35-40. Remarkable strides have been made in the treatment of flexor tendon injuries in the past 40 years. Advances in the understanding of flexor tendon anatomy, nutrition, healing, and biomechanics has significantly improved the treatment of these challenging injur...

...................................................................................................................................................... 1 POPULÄRVETENSKAPLIG SAMMANFATTNING ............................................................................ 2 LIST OF PAPERS ......................................................................................................................

In this study, the role of local injection of butyric acid (BA) with autogenous omental graft was evaluated in healing of experimental Achilles tendon injury in rabbits. Nine adult male New Zealand rabbits were anesthetized and a partial thickness tenotomy was created on both hindlimbs. In treated group, omental graft was secured in place using BA soaked polygalactin 910 suture. In control grou...

INTRODUCTION: A tendon graft is indicated when a flexor tendon repair fails, or when tendon rupture or tendon transfer requires prolongation of the muscle-tendon unit. The effect of hyaluronic acid (HA) on flexor tendon repair has been investigated in many animal and clinical studies. Exogenously applied HA may prevent adhesion formation between the flexor tendon and surrounding tissue followin...

Tendons transmit forces from muscle to bone and provide the joint function and ligaments transmit forces from bone to bone and provide joint stability. Tendon and ligament injuries have high incidence and management of tendon and ligament injuries is technically demanding because the healing response of these soft connective tissues is low. In addition, number of the available options to be con...

...................................................................................................... 3 Introduction................................................................................................ 5 Healing phases.............................................................................................................. 5 Factors that influence tendon healing....................

BACKGROUND The recent discovery of residing tendon stem/progenitor cells has triggered a growing interest in stem cells as a useful tool in tendon repair. Our knowledge of their involvement in naturally healing tendons is, however, sparse. The aim of this study was to identify and determine stem/progenitor cells in relation to different healing phases and regions in a rat model of Achilles tend...

BACKGROUND Clinical tendon injuries represent serious and unresolved issues of the case on how the injured tendons could be improved based on natural structure and mechanical strength. The aim of this studies the effect of aquatic activities and alogenic platelet rich plasma (PRP) injection in healing Achilles tendons of rats. METHODS Forty rats were randomly divided into 5 equal groups. Seve...

Tendon rupture is a common injury. Inadequate endogenous repair often leaves patients symptomatic, with tendons susceptible to re-rupture. Administration of certain growth factors improves tendon healing in animal models, but their delivery remains a challenge. Here we evaluated the delivery of TGF-β1 to tendon defects by the implantation of genetically modified muscle grafts. Rat muscle biopsi...