PURPOSE To analyze the results of the use of intra-articular cultured autologous bone marrow-derived mesenchymal stem cell (MSC) injections in conjunction with microfracture and medial opening-wedge high tibial osteotomy (HTO). METHODS Fifty-six knees in 56 patients with unicompartmental osteoarthritic knees and genu varum were randomly allocated to the cell-recipient group (n = 28) or contro...

INTRODUCTION It is difficult to counsel the anterior cruciate ligament (ACL) deficient patient considering surgical reconstruction on the likelihood of eventual return to sports as information on this is lacking, especially in the Asian context. We wanted to determine how many of our patients who had ACL surgery returned to their previous levels of sports, 5 years after their surgery. For those...

Purpose: To analyze the results of the use of intra-articular cultured autologous bone marrowederived mesenchymal stem cell (MSC) injections in conjunction with microfracture and medial opening-wedge high tibial osteotomy (HTO). Methods: Fifty-six knees in 56 patients with unicompartmental osteoarthritic knees and genu varum were randomly allocated to the cell-recipient group (n 1⁄4 28) or cont...

BACKGROUND Several clinical studies have reported on cell-based treatment using mesenchymal stem cells (MSCs) for cartilage regeneration in knee osteoarthritis (OA). However, little is known about the factors that influence the clinical outcomes after surgery. PURPOSE/HYPOTHESIS This study aimed to investigate the clinical outcomes of MSC implantation in patients with knee OA and assess the f...

STUDY DESIGN A retrospective, long-term follow-up study. OBJECTIVES To find out whether incidental durotomy in lumbar disc surgery is associated with long-term sequelae. SUMMARY OF BACKGROUND DATA Incidental durotomy is a frequent complication during spinal surgery. Little is known about the clinical long-term outcome. METHODS The study population comprised 1,280 patients who underwent st...

Previous case reports have documented the successful use of allograft for extensor mechanism reconstruction. We hypothesized that extensor mechanism reconstruction with allograft would restore extensor power and allow patients to return to a relatively high activity level. Between 2000 and 2007, 17 patients (18 knees) underwent extensor mechanism reconstruction with either nonirradiated Achille...

PURPOSE The aim of this study was to compare the effectiveness of 2 different meniscal scaffolds in treating patients with irreparable partial medial meniscal tear and patients complaining of pain in the medial compartment of the knee due to a previous partial medial meniscectomy. Based on previous studies, we hypothesized that both the scaffolds are effective in improving clinical outcomes in ...

BACKGROUND Malignant bone tumors of the lower extremity are more frequently found in children and adolescents than in adults. Modern treatment regimens led to high limb salvage rates and offer the choice between endoprosthetic replacement and rotationplasty in many cases. Rotationplasty has proven to be an effective, highly functional option in short- and mid-term studies. Aim of this study was...

BACKGROUND A patellar dislocation is a common knee injury in the young, athletic patient population. Recent trends indicate that the use of long-term nonoperative treatment is decreasing, and surgical intervention is more commonly recommended for those patients who fail initial nonoperative management with recurrent patellar dislocations. Medial patellofemoral ligament (MPFL) reconstruction has...

BACKGROUND Determination of appropriate treatment options for adult osteochondritis dissecans is difficult, as most published papers on surgical osteochondritis dissecans treatment report outcomes in a population consisting of both adult and juvenile patients. PURPOSE This study examines the outcomes of surgical procedures in patients with adult osteochondritis dissecans. STUDY DESIGN Case ...