HP and HPR are related and contiguous genes in strong linkage disequilibrium (LD), encoding haptoglobin and haptoglobin-related protein. These bind and chaperone free Hb for recycling, protecting against oxidation. A copy number variation (CNV) within HP (Hp1/Hp2) results in different possible haptoglobin complexes which have differing properties. HPR rs2000999 (G/A), identified in meta-GWAS, i...

Interventions of cardiovascular disease should be implemented in early ages. But most studies were performed in middle aged or elderly adults because of the low prevalence in young, especially for women. We investigate the association between metabolic risk factors and subclinical atherosclerosis in young asymptomatic women adults, using carotid intima-media thickness (CIMT) as a marker of the ...

Objective Published studies suggest that the effects of curcumin on blood lipids in adults are controversial, and it is unclear whether there a dose response to lipid changes following supplementation. Therefore, we conducted systematic review meta-analysis randomized controlled trials (RCTs) evaluate triglycerides (TG), total cholesterol (TC), low-density lipoprotein (LDL), high-density (HDL) ...

Abstract To analyze the relationship between systemic lipid profile levels and meibomian gland dysfunction (MGD) subtype in Korea. The ophthalmic data of 95 eyes serum profiles patients were reviewed. These factors compared with those general population using from Korean National Health Nutrition Examination Survey (KNHANES), which evaluated 2,917 subjects. Of these, comparison group (1:5 ratio...

Introduction: Most of previous studies on dyslipidemia among pilots were cross-sectional surveys which cannot explore the temporal trend of dyslipidemia, and these studies were normally conducted at least five years ago. In addition, studies focusing on pilots in Southwest China are scarce. This study aimed to describe the prevalence of and trends in dyslipidemia among pilots f...

A cohort study of 90 days was designed to explore the hypercholesterolemic associated blood pressure with intake extruded flaxseed powder (EFSP) fortified yogurts. The subjects were distributed into two groups (1 and 2), then samples taken. Descriptive statistics used for comparison between groups. significant increase in serum total cholesterol (TC) (6.330.48 6.510.04 mmol/dL) low-density lipi...

BACKGROUND Data regarding the impact of different lipid measures on cardiovascular diseases (CVD) and mortality events is not consistent. We aimed to evaluate the relationship between different lipid parameters and incident CVD and mortality events in an Iranian population over a median follow-up of 11.9 years. METHODS The study was conducted on 2532 men and 2986 women aged ≥ 40 years. Multiv...

BACKGROUND Low plasma concentrations of coenzyme Q10 (CoQ10) have been associated with concentration of lipoproteins and other factors contributing to coronary heart diseases. OBJECTIVES The present investigation aimed to improve the blood pressure and serum lipoproteins concentration in patients with myocardial infarction (MI) by CoQ10 supplementation. PATIENTS AND METHODS In this randomiz...

Human paraoxonase (PON1) exists in 2 major polymorphic forms and has been shown to protect LDL and HDL against oxidation. The aim of this study was to assess the differences between subjects at increased risk of cardiovascular disease (CVD), taking into account the effects of PON1-Q192R and PON1-L55M polymorphisms on 1) basal serum arylesterase activity, lipid peroxidation (LPO), and LDL-choles...