BACKGROUND Late-onset Alzheimer's disease (AD), a genetically heterogeneous neurodegenerative disorder, is the most common form of dementia in people over 65 years old. The role of vitamin D in neuropsychiatric and neurodegenerative disorders such as AD has been supported by epidemiologic investigations and animal models, as well. We examined the association of the vitamin D receptor (VDR) gene...

in this paper taqi modarresi’s life and his works are discussed briefly. he is one of the early persian writers in diaspora who left iran decades before the islamic revolution.  his novels have been published both in english and persian. azra-ye khalvatneshin [the virgin of solitude], which was published posthumously in an english translation in 2008 and in the original persian in 2010, both in...

Background: Type 2 diabetes mellitus that characterized by insulin resistance and it is a risk of many diseases the impact genetic factors on well documented. Vitamin D receptor (VDR) gene polymorphisms have been linked to T2DM. In this study, we analyzed relation between TaqI ApaI VDR T2DM subjects using PCR-RFLP method in Kurdish patients.

Source and Description: G2—2 E is a single copy 200 bp subfragment of G2 cloned into the EcoRV site of Bluescript KSII(+). Clone G2 was isolated from a library highly enriched for (TTAGGG)n-associated sequences (1). Polymorphisms: TaqI identifies a two allele polymorphism as assessed in 29 unrelated Caucasians. Allele Size No. of Chromosomes Frequency Al 900 bp 31 (0.54) A2 700 bp 27 (0.46) Pst...

Vitamin D deficient rickets is prevalent in Turkey and a considerable number of children are at risk of growth retardation, impaired bone formation and fracture. In order to check whether vitamin D receptor (VDR) gene polymorphism relates to the vitamin D deficient rickets, we analyzed VDR gene FokI, TaqI and ApaI polymorphisms in 24 Turkish vitamin D deficient rickets patients and 100 healthy ...

A cDNA for coagulation factor XII has been used to investigate the presence of gene lesions and restriction fragment length polymorphisms in two brothers with Hageman trait and their family. A TaqI polymorphic fragment has been found in the two propositi and in 11 members of the paternal lineage. This polymorphism, absent in the normal population, is correlated with the reduction of factor XII ...

Bovine leukocyte adhesion deficiency (BLAD) is a genetically transmitted disease and inherited as an autosomal recessive defect. Keeping this in view the present study was conducted to estimate incidence of carrier animals in a herd of breeding bulls for mutation in Integrin â2 gene, reared at Frozen Semen Bull Station (FSBS), Haringhata, Nadia, West Bengal, India. A total of 80 bulls of differ...