Transgenic mice containing a ren-2 promoter T-antigen fusion construct (TAG+) develop renal vascular hypertrophy and hyperplasia associated with markedly suppressed renal renin mRNA, renal renin content, and plasma renin concentration. These animals are normotensive. In the present study, the renal and cardiovascular systems are characterized, revealing some surprising findings. Not only are th...

Madhavan and Khetan raise questions about our paper that were largely addressed in the original publication. First, we reiterate that it is not possible to draw direct conclusions about the cell of origin of human retinoblastoma on the basis of data in the TAg-RB mouse model; unfortunately, we lack the unambiguous marker of the tumor lineage in human retinoblastoma that TAg provides in the mous...

We describe herein a new transgenic mouse tumor model in which fibroblast growth factor (FGF) receptor activity is selectively inhibited. Tyrp1-Tag mice that develop early vascularized tumors of the retinal pigment epithelium were crossed with tyrp1-FGFR1-DN mice that express dominant-negative FGF receptors in the retinal pigment epithelium to generate bigenic mice. Initial angiogenesis-indepen...

The aim of this paper is to analyse the wh movement for Romanian in TAG formalisrn. Romanian shares free extractibility from tensed clauses with its Rornance sister languages and it has borrowed multiple wh-fronting from the slavic languages. These features of Rornanian are quoted by Kroch (1989) frorn Comorovsky (1986) , where he justifies the analysis of extractions in TAG. This formalism all...

This brief review is just that a far from definitive overview of the development of tagging as a tool for studying marine mammals, based on a quick and superficial review of the literature. My intention is simply to give participants a broad appreciation for some of the questions that have been addressed by tagging, what kinds of challenges have arisen in designing and applying tags to wild mar...

The European Commission Consumers, Health, Agriculture and Food Executive Agency (CHAFEA) call for tender to carry out two studies on the added value of strategic and life-course approach to vaccination , and on shortcomings related to low vaccination in healthcare workers, respectively, will close on 13 September 2016. According to the tender document 'each study has to include a representativ...

We propose strategic games wherein the strategies consist of players asking each other questions and answering those questions. We study simplifications of such games wherein two players simultaneously ask each other a question that the opponent is then obliged to answer. The motivation for our research is to model conversation including the dynamics of questions and answers, to provide new lin...

AnswerFinder is a framework for the development of question-answering systems. AnswerFinder is currently being used to test the applicability of graph representations for the detection and extraction of answers. In this paper we briefly describe AnswerFinder and introduce our method to learn graph patterns that link questions with their corresponding answers in arbitrary sentences. The method i...

. This paper discusses active teaching and learning strategies that have been used in the TeNeT Online tutorials [1]. The focus of these tutorials is to enable rural students to pass the Standard X examination. The highlight of the tutorial is the use of the Question and Answer format. This problem-solving approach is evident in its three-pronged format: Learn, Practice and Test. Every module i...

This study compared two methods for identifying troublesome examination questions: a postexam student "challenge committee" process and a "question citation" procedure allowing students to identify troublesome questions during an exam. Challenged and cited questions on eight examinations given to second-year medical students were compared with respect to the percentage of correct responses (%CR...