The aim of this study was to analyze the changes in complements C3 and C4 and C-reactive protein (CRP) in patients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA), and to evaluate the role of these indices in the differential diagnosis of SLE and RA. The first 347 patients with SLE, 382 patients with RA and 66 patients with erythema nodosum were selected for the measuremen...

various neurological complications occur in primary or secondary antiphospholipid syndrome (aps) consisting of cerebrovascular attacks, ocular events, dementia, seizure, chorea, and transverse myelopathy that are all related to the titer of antiphospholipid antibodies (apl). we report a patient with chorea and retinal vessel occlusion as manifestations of systemic lupus erythematosus (sle) and ...

systemic lupus erythematosus (sle) is a chronic autoimmune disease which results in damage to various organs. some animal studies have revealed that activation of toll-like receptors (tlrs) is important in the pathogenesis of sle. in the present study, the percentage of different immune cell subsets in 35 sle patients and 38 control subjects was analyzed by flow cytometry. we also assessed the ...

objective(s): systemic lupus erythematosus (sle) is a multi-factorial autoimmune disease which may be characterized by t lymphocytes dysfunctions. th17 cells have been identified as new effector cells, which play an important role in the pathogenesis. in recent years, immunomodulatory effect of vitamin d3 has been noticed. in the present experiment, the effect of vitamin d3 on the expression of...

isolated hematuria and its association with proteinuria, and urinary cast and systemic lupus erythematosus (sle) disease activity, and decision for renal biopsy is a dilemma for physician in sle patients. the aim of this study was to investigate 1. whether isolated hematuria is associated with active sle, 2. to determine duration between hematuria and proteinuria and urinary cast, and 3. to det...

aim and background: systemic lupus erythematosus (sle) is a chronic autoimmune disease usually associated with high levels of pain and impairment in different systems, producing high levels of stress in patients who suffer from it. the purpose of this study was to consider the effectiveness of cognitive-behavioral stress management (cbsm) therapy on stress of female patients with sle. methods a...

background: diagnosis and treatment of neuropsychiatric lupus is still a major challenge in clinical practice. we investigated the association between depression and anti-ribosomal p (anti-p) antibodies in a sample of iranian patients with systemic lupus erythematosus (sle). materials and methods: th is cross-sectional study was conducted on adult patients with sle referring to a referral out-p...

a 21 years old woman presented with a history of sle and skin lesions on the arms, trunk, and abdomen. the left gluteal region was ulcerated and painful and occasionally extruded a chalky white material. the patient referred from rheumatology department for osteomyelitis assessment. on physical examination the patient had hard, nontender lesions on the proximal arms, lower abdomen and lower bac...

objective: hla-g is a nonclassical major histocompatibility complex antigen and is expressed as seven isoforms, including four membrane bound (hla-g1 to –g4) and three soluble (hla-g5 to –g7) forms. the pattern of selective expression of hla-g transcripts in tissues shows the existence of a tight transcriptional control on the gene expression. it has been revealed that cytokines including inter...

background and objectives: this research study was conducted to determine the correlation between the clinicopathologic features and the outcome of membranous nephropathy. materials and methods: data were retrospectively reviewed from all patients with a diagnosis of membranous nephropathy. demographic, initial laboratory, and clinical findings were collected and the biopsy specimens were revie...