Syphilis has been intricately linked with HIV because of shared transmission pathways and these infections promote each other’s transmission. In addition, infection may change the clinical presentation management syphilis lesions. Initially, epidemic had improved safe sex practices among men who have (MSM), but subsequent effective treatment prophylaxis strategies, resulted in behavioural disin...

Syphilis diagnosis is based on clinical observation, serological analysis, and dark-field microscopy (DFM) detection of Treponema pallidum subsp. pallidum, the etiological agent of syphilis, in skin ulcers. We performed a nested PCR (nPCR) assay specifically amplifying the tpp47 gene of T. pallidum from swab and blood specimens. We studied a cohort of 294 patients with suspected syphilis and 35...

INTRODUCTION Syphilis has made a dramatic resurgence in China during the past two decades. During the Cultural Revolution (1966e76), sexually transmitted infections (STI) were so uncommon that they were removed from standard Chinese medical training curricula. As China’s market economy expanded during 1980s economic reforms, reported STI, including syphilis infection, quickly re-appeared. An ev...

OBJECTIVE: To assess the prevalence of syphilis among patients at a tertiary referral center in Turkey and determine the need for antenatal syphilis screening based on the results. STUDY DESIGN: A retrospective cohort study based on patient data obtained from a tertiary referral center in Turkey. Serological syphilis screening using the Venereal Disease Research Laboratory (VDRL) was performed ...

BACKGROUND Syphilis is a global health concern disproportionately affecting HIV-infected populations. In Alberta, Canada, the incidence of syphilis in the general population has recently doubled with 25% of these infections occurring in HIV-infected patients. The Southern Alberta HIV Clinic (SAC) and Calgary STI Program (CSTI) analyzed the epidemiologic characteristics of incident syphilis infe...

Syphilis is a health problem of increasing incidence in recent years that may have severe complications if not diagnosed and treated at an early stage. There are many diagnostic tests available for syphilis, but there is no gold standard, and diagnosis therefore usually relies upon a combination of tests. In this multicenter study, we evaluated the treponemal Elecsys syphilis assay for use in t...

Up to the present time there is no convenient and exact division of syphilis seizures into certain groups, which would make it possible understand essence this or that suffering organism on basis disease: Biett, e.g., divides all their morphological features, Risord - appearance, Virchow, Brensprung, Bazin, Leloir, Zeissl others mainly take account qualitative character pathological anatomical ...

Patients with HIV infection may develop common diseases with atypical clinical features. HIV infection may change the classic clinical course of syphilis and increase the incidence of a subtype of secondary syphilis named malignant syphilis. A homosexual patient with HIV infection consulted us about a one-month history of general malaise and widespread cutaneous ulcerative lesions, some with th...

INTRODUCTION Syphilis in the UK continues to rise, particularly among men who have sex with men. In 2014, there was a 46% increase in syphilis in this risk group.1 Syphilis is a major problem in some parts of the world including Eastern Europe and is also seen in heterosexual men and women. Syphilis has also been diagnosed in white British individuals with no obvious risk factors. Two rapidly e...

Congenital syphilis is still a cause of perinatal morbidity and mortality. Untreated maternal infection leads to adverse pregnancy outcomes, including early fetal loss, stillbirth, prematurity, low birth weight, neonatal and infant death, and congenital disease among newborns. Clinical manifestations of congenital syphilis are influenced by gestational age, stage of maternal syphilis, maternal ...