INTRODUCTION Ultrasonography (US) has better sensitivity than clinical evaluation for the detection of synovitis in early rheumatoid arthritis (RA). Patients presenting with arthralgia and a positive anti-citrullinated protein antibodies (ACPA) and/or Rheumatoid Factor (IgM-RF) status are at risk for developing RA. In the present study, US utility and predictive properties in arthralgia patient...

OBJECTIVE To assess whether the presence of structural osteoarthritis (OA) features over as many as 4 years prior to incident radiographic OA increases the risk of radiographic OA in a nested, case-control design. METHODS We studied 355 knees from the Osteoarthritis Initiative cohort that developed radiographic OA before the 48-month visit. They were matched one-to-one by sex, age, and contra...

intraepiphyseal location of an osteoid osteoma is extremely rare with few cases reported in the literature. they are often present with various atypical and nonspecific clinical features. synovitis of adjacent joint is common and along with chronic inflammation could be misinterpreted as rheumatoid arthritis. initial plain radiographs are often not diagnostic and further radiologic evaluation w...

This case report is concerned with a 30 year old patient diagnosed with pigmented villonodular synovitis (PVNS) in the knee. The patient underwent an orthopedic surgical operation to remove the lesions. PVNS is a rare proliferative disorder, mostly benign and affecting the knee; its aetiology remains unclear. It represents a medical challenge because of non-specific symptoms that delay the diag...

To cite: Atik A, Ozyurek S, Sivrioglu AK, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2013009353 DESCRIPTION A 23-year-old man who had sustained a minor twisting injury 10 days prior, presented with right knee pain and swelling. There was no history of joint problems, infection or bowel problems, nor was there a family history of arthritis. Physical exa...

We read with deep interest the article by Atukorala et al aimed at determining if synovitis precedes the development of radiographic knee osteoarthritis (ROA). This nested case–control study suggested that effusion-synovitis and Hoffa-synovitis strongly predicted the development of incident ROA. We really appreciate the work which was done by the authors. The findings supported the potential ro...

Pigmented villonodular synovitis (PVNS) is a rare benign neoplastic proliferation of synovial tissue which is typically localised and usually responds well to surgery and/or radiotherapy. We present a case of unusually aggressive of PVNS of the hip in a 73-year-old woman.