The antigenic phenotype of human synovial lining cells in normal and hyperplastic synovium intima was determined with a panel of monoclonal antibodies directed against a large number of well defined myeloid (macrophage/granulocyte associated) antigens. Synovial lining cells express numerous macrophage associated antigens, including CD11b (CR3), CD13, CD14, CD16 (FcRIII), CD18, CD32 (FcRII), CD4...

Cell-cell interactions play an important role in the development of cartilage. Heterologous and homologous cell-cell interactions are critical for chondrogenic differentiation during development. Cell-cell interactions in the formation of fracture callus and cartilage neoplasia also invoke the process of cartilage differentiation. We have investigated cell-cell interactions between articular ch...

In vivo effects of Yersinia enterocolitica 0:3 lipopolysaccharide (prepared from bacteria grown at 253C and 373C) were investigated after intraperitoneal (i.p.) and intraarticular (i.a.) injection in rats during 30 days of examination. The persistence of endotoxin in the peritoneal and the synovial cavities was demonstrated by the immunofluorescence technique. Peritoneal and synovial exudative ...

Synovial sarcoma is a distinctive soft tissue neoplasm, most commonly seen in the extremities of young adults. Mediastinal synovial sarcoma is a well-documented entity; however, in many cases, the differentiation between this and other spindle cell tumours may be difficult, especially in monophasic tumours. Unlike most pleuropulmonary synovial sarcomas which are well circumscribed, mediastinal ...

In vivo effects of Yersinia enterocolitica 0:3 lipopolysaccharide (prepared from bacteria grown at 25 degrees C and 37 degrees C) were investigated after intraperitoneal (i.p.) and intraarticular (i.a.) injection in rats during 30 days of examination. The persistence of endotoxin in the peritoneal and the synovial cavities was demonstrated by the immunofluorescence technique. Peritoneal and syn...

providing suitable analgesia following diagnostic and therapeutic arthroscopic surgeries, that areconsidered to cause some degree of postoperative pain, is a necessity in equine practice. the aim of thepresent study was to evaluate the equine synovial fluid biochemical and cytological changes as well asclinical assessments of the joint following intra-articular administration of ketamine. six a...

Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation in joints, associated with synovial hyperplasia and with bone and cartilage destruction. Although the primacy of T cell-related events early in the disease continues to be debated, there is strong evidence that autoantigen recognition by specific T cells is crucial to the pathophysiology of rheumatoid synov...

Background Rheumatoid arthritis (RA) is a chronic autoimmune disorder that mainly affects the joints. The synovium primary site of inflammatory process, in which local immune response develops. Peripheral helper T cells (Tph) are population CXCR5 - PD1 hi CD4 + thought to provide help for ectopic B cell response. However, whether there heterogeneity among Tph not clear. Objectives To identify f...

Poorly differentiated synovial sarcomas are diagnostically challenging soft tissue tumors. They can be indistinguishable from other "small blue cell tumors" based on morphology and even immunohistochemical studies. Here we report a rare case of poorly differentiated metastatic synovial sarcoma to lung without known primary, diagnosed with molecular genetic analysis. The tumor was negative for E...

pared to normal synovial cells. This little book reviews these and other measurements in plasma, urine, synovial fluid, tissue extracts and synovial cell culture. The chapter on hormones is notable for its statement that prednisolone is the only drug which can halt the erosive progress of rheumatoid arthritis. This is certainly not the orthodox view of most rheumatologists, and its emphasis cas...