During the period of 1 January 1998 to 31 December 2012, the health care records of 153,172 active component service members documented at least one health care encounter with a diagnosis of "syncope and collapse" (overall incidence rate of 7.2 cases per 1,000 person-years). The annual incidence rates rose by 89 percent during the period. During the 15-year surveillance period, there were 4,954...

AIM To evaluate the incidence, diagnostic yield and safety of implantable loop recorders (ILRs) in patients with or without structural heart disease (SHD). METHODS AND RESULTS Two-hospitals, observational, prospective study in consecutive patients with unexplained syncope who underwent an ILR implantation. Between November 1997 and December 2002, a total of 2052 patients with syncope were eva...

OBJECTIVES We sought to establish what historical findings are predictive of the cause of syncope. BACKGROUND The clinical features of the various types of syncope have not been systematically investigated. METHODS Three hundred forty-one patients with syncope were prospectively evaluated. Each patient was interviewed using a standard questionnaire. A cause of syncope was assigned using sta...

BACKGROUND Due to lack of efficacy in recent trials, current guidelines for the treatment of neurally-mediated (vasovagal) syncope do not promote cardiac pacemaker implantation. However, the finding of asystole during head-up tilt -induced (pre)syncope may lead to excessive cardioinhibitory syncope diagnosis and treatment with cardiac pacemakers as blood pressure is often discontinuously measur...

INTRODUCTION Our aim was to determine the characteristics of patients presenting with syncope at a tertiary care hospital in Karachi, Pakistan. METHODS A review of medical records was conducted retrospectively at the Department of Medicine, Aga Khan University Hospital, Karachi. Patients aged 16 and above, admitted from January 2000 to December 2005 with the diagnosis of syncope made by the a...

PURPOSE The gender difference of neurally mediated syncope is not well defined in a large patient population. The aim of this study was to evaluate the gender difference of clinical manifestations in patients with neurally mediated syncope who underwent head-up tilt test. MATERIALS AND METHODS The medical records of 1,051 consecutive patients with two or more episodes of syncope, who were dia...

AIMS The aim of this study was to evaluate the effect of introducing a European Society of Cardiology guideline-based Integrated Care Plan (ICP) for Syncope on hospital admissions and referral patterns to an outpatient Syncope Management Unit, of patients presenting to an Emergency Department (ED) with a syncopal episode and to determine the underlying causes of syncope. METHODS AND RESULTS T...

BACKGROUND The primary aim and central hypothesis of the study are that a designated syncope unit in the emergency department improves diagnostic yield and reduces hospital admission for patients with syncope who are at intermediate risk for an adverse cardiovascular outcome. METHODS AND RESULTS In this prospective, randomized, single-center study, patients were randomly allocated to 2 treatm...

Syncope is a frequent clinical manifestation and represents 1–2% of emergency room visits and frequently leads to hospital admission and expensive and frequently unnecessary diagnostic tests. The cause of syncope is frequently reflex mediated, and particularly vasovagal responses closely followed by orthostatic hypotension and drug-induced syncope are the main causes. By and large, the prognosi...

The incidence of syncope peaks in early working age, yet there are few data on its impact on occupational safety and employment. The consequences of syncope in the workplace are important to establish because the lifetime prevalence of syncope is 35%, and one third of patients experience recurrent syncope within few years. Approximately 3.4 million workers are treated in emergency departments f...