The majority of clinical studies on pain, fatigue, and depression associated with cancer are focused on one symptom. Although this approach has led to some advances in our understanding of a particular symptom, patients rarely present with a single symptom. Therefore, even though research focused on single symptoms needs to continue, it is imperative that symptom management research begins to f...

Symptom exaggeration or fabrication occurs in a sizeable minority of neuropsychological examinees, with greater prevalence in forensic contexts. Adequate assessment of response validity is essential in order to maximize confidence in the results of neurocognitive and personality measures and in the diagnoses and recommendations that are based on the results. Symptom validity assessment may incl...

This thesis consists of four research papers presenting a microdata analysis approach to assess and evaluate the Parkinson’s disease (PD) motor symptoms using smartphone-based systems. PD is a progressive neurological disorder that is characterized by motor symptoms. It is a complex disease that requires continuous monitoring and multidimensional symptom analysis. Both patients’ perception rega...

Symptom validity testing (SVT) has become a major theme of contemporary neuropsychological research. However, many issues about the meaning and interpretation of SVT findings will require the best in research design and methods to more precisely characterize what SVT tasks measure and how SVT test findings are to be used in neuropsychological assessment. Major clinical and research issues are o...

Patient-reported outcomes regarding symptom burden may provide valuable information in addition to physician assessment. Systematic collection of patient-reported outcomes may be an important metric to identify unmet needs and improve quality of patient care. To understand common symptoms of patients seen in radiation oncology clinic, we examined the prospectively collected modified Edmonton Sy...

O ne of the most vexing problems for a pediatric hematologist is the appropriate investigation of mild bleeding symptoms. Bruising and epistaxis are typical features of childhood yet frequent reasons for referral, and are often difficult to quantify and precisely categorize as either normal or suspicious. There are a significant number of individuals in the general population who report non-spe...

BACKGROUND 520 CONTENTS Symptoms of incontinence are common, particularly amongst older people, and, at any age, incontinence can have a severe impact on the quality of life of some individuals. A number of treatments for incontinence are available, most of which aim to reduce the occurrence of incontinent episodes or to limit the impact of the disorder on everyday life. In research and clinica...

Background: This study investigated the applicability of the Post-traumatic Stress Disorder Symptom Scale (PSS) in a group of adolescents who had been directly involved in a disaster in Tehran. Method: Participants were 20 adolescents who had survived a boat sinking in Tehran's city park in 2002. The assessment measures used were the Post-traumatic Stress Disorder Symptom Scale (PSS) and clini...