Abstract Funding Acknowledgements Type of funding sources: None. 【Background】 Patients with pulmonary hypertension (PH) suffer from poor exercise capacity due to impaired oxygenation or reduced cardiac output. However, the relationship between and physical functions remains unclear. 【Purpose】 The purpose this study is investigate in hypertension. 【Methods】 From February 2018 June 2020, 94 patie...

Abstract Introduction Body fluid status can be determined by plasma volume and extracellular water to total body (ECW/TBW) ratio is a well-known parameter associated with survival in patients chronic heart failure (1–3). However, its prognostic impact pulmonary arterial hypertension (PAH) thromboembolic (CTEPH) not fully understood. Methods 409 PAH CTEPH who entered the Giessen PH registry were...

Statement of problem: Spatial-resolved near-infrared spectroscopy enables non-invasive continuous measurement of " tissue oxygenation index " (TOI), which correlates to mixed venous oxygenation (SvO2). The aim of the present study was to compare cerebral TOI and peripheral TOI. Statement of methods: Repeated simultaneous measurements on right forehead and calf, were performed in 10 neonates wit...

BACKGROUND AND OBJECTIVES Different experimental models have been used to illustrate hemodynamic and metabolic changes during hemorrhagic shock. This study aimed at observing hemodynamic and metabolic behaviors during a sequential and progressive model of hemorrhagic shock in dogs to determine which indices are earlier changed. METHODS The study involved 13 dogs under total intravenous anesth...

Background: Measurement of central venous-to-arterial CO2 difference (p(cv-a)CO2) as an estimate of mixed venous-to-arterial CO2 difference (p(v-a)CO2) has been recommended as an supplementary parameter to identify the inadequacy of tissue oxygenation in septic and postoperative non-cardiac high risk surgery patients. This study investigates the agreement between p(cv-a)CO2 and p(v-a)CO2, and e...

Continuous monitoring of mixed venous oxygen saturation (SvO2) and arterial oxygen saturation (SaO2) was used to guide cardiovascular and pulmonary physiologic manipulations in three patients. An index, termed the "shunt index" (SI), of venoarterial admixture (Qva/Qt) was calculated at the bedside. SI correlated significantly in each patient with Qva/Qt (p less than .01). In one of the patients...

BACKGROUND Unvented chest seals (CSs) are currently recommended for the management of penetrating thoracic injuries in the battlefield. Since no supporting data exist, we compared the efficacy of a preferred unvented with that of a vented CS in a novel swine model of pneumothorax (PTx). METHODS An open chest wound was created in the left thorax of spontaneously air-breathing anesthetized pigs...