نتایج جستجو برای: sulfur mustard gas
تعداد نتایج: 279932 فیلتر نتایج به سال:
Background: Sulfur mustard is one of the chemical warfare gases that has been known as a vesicant or blistering agents. It is a chemical alkylating compound agent that can be frequently absorbed through skin, respiratory system, genital tract, and ocular system. This study was done to pathologically analyze the microscopic pancreatic lesions in cadavers. Methods: This case series study was per...
Introduction: IFN-γ is one of the most important cytokines in the development of chronic inflammatory diseases such as asthma and COPD. The IFN-γ promoter methylation at CpG islands could be altered by various chemical and toxic substances which may have a role in the incidence of chronic pulmonary diseases and its severity. Thereby, the present study was aimed to evaluate the effect of sulfur ...
Background and Aim: Among late complications in mustard gas or sulfur mustard (SM) casualties, respiratory problems, especially chronic bronchitis and pulmonary fibrosis are the greatest causes of longterm disability. Cyclosporine has anti-inflammatory effects and is used in other pulmonary fibroses due to other factors. Thus, with respect to the role of oxidative stress in the pathogenesis of...
a colorimetric method for detection and assay of mustard gas in urine after addition of thymolphthalein is reported. the detection limit was 80 ng/ml of llrine. mustard gas could also be detected in urine after extraction with gas chromatography using fid detector. the detection limit was 10 ng/ml. in addition, thiodiglycol, a metabolite of mustard gas, could be converted to mustard with concen...
background: sulfur mustard (sm) is an incapacitating chemical warfare agent, which has been widely employed in particular regions including iran. we investigated and reported delayed biochemical and hematological complications of sm in severely toxic iranian veterans 23 years after exposure. materials and methods: forty-two iranian veterans, residents of khorasan razavi, poisoned by sm, and suf...
Keywords: Sulfur mustard, Respiratory injury, health status, disease
OBJECTIVE The purpose of this study was to examine whether the degree of air trapping in high resolution computed tomography (HRCT) of patients with histories of sulfur mustard gas exposure during suspended full expiration correlated with various parameters of the cardiopulmonary exercise test as the gold standard for assessment of pulmonary function. METHODS In this analytic study 75 male pa...
A colorimetric method for detection and assay of mustard gas in urine after addition of thymolphthalein is reported. The detection limit was 80 ng/ml of llrine. Mustard gas could also be detected in urine after extraction with gas chromatography using FID detector. The detection limit was 10 ng/ml. In addition, thiodiglycol, a metabolite of mustard gas, could be converted to mustard with ...
Among the blistering (vesicant) chemical warfare agents (CWA), sulfur mustard is the most important since it is known as the “King of chemical warfare agents”. The use of sulfur mustard has caused serious damages in several organs, especially the eyes, skin, respiratory, central and peripheral nervous systems after short and long term exposure, incapacitating and even killing people and troops....
Release of sulfur mustard-modified DNA bases by Escherichia coli 3-methyladenine DNA glycosylase II.
The toxic effects of sulfur mustard have been attributed to DNA modification with the formation of 7-hydroxyethylthioethyl guanine, 3-hydroxyethylthioethyl adenine and the cross-link, di-(2-guanin-7-yl-ethyl)sulfide. To investigate the action of bacterial 3-methyladenine DNA glycosylase II (Gly II) on these adducts, calf thymus DNA was modified with [14C]sulfur mustard and used as a substrate f...
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