The presence of antimicrobial agents in edible tissues of food-producing animals remains a major public health concern. Probabilistic modeling techniques incorporated into a physiologically based pharmacokinetic (PBPK) model were used to predict the amounts of sulfamethazine residues in edible tissues in swine. A PBPK model for sulfamethazine in swine was adapted to include an oral dosing route...

The molecular structures of sulphonamides are interesting for evaluating their mobility in soils and preparing composite complexes optimizing the use these drugs. In this work, several arylsulfonamides along with conformational analysis tautomerism were investigated theoretically. spectroscopical properties arylsulfonamides, also studied at level by using a computational modeling quantum mechan...

Kinetic Monte Carlo modeling was employed to investigate the kinetics and photodecomposition mechanism of sulfamethazine, ciprofloxacin, sulfathiazole, amoxicillin antibiotics by photo-Fenton process (iron(III) citrate/hydrogen peroxide in presence UV irradiation). The reaction kinetic mechanisms each degradation mentioned above have been achieved. rate constants values for step (including anti...

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