conclusions the addition of 2.5-3 mcg sufentanil to 15 mg 0.05% bupivacaine maintained the patient’s hemodynamic stability similar to fentanyl. intrathecal sufentanil added to bupivacaine,when compared with fentanyl, may lead to prolonged duration of analgesia, facilitate the spread of the sensory block, increase mean spo2 levels, and reduce overall side effects. background the addition of intr...

of 0.2 mgzkgzh are presented in Fig. 1, B and C, respectively. The concentration of SF recovered in the plasma sample was 0.80 mg/L. In conclusion, SPE before GC-MS represents a convenient method for quickly obtaining clean extracts with optimum recoveries and could be an accurate analytical tool for the monitoring of SF concentrations in plasma samples during pharmacokinetic studies. Reference...

BACKGROUND Most patients experience some degree of pain during extracorporeal shock waves lithotripsy (ESWL). AIM The aim of this study was to evaluate the effect of target-controlled infusion (TCI) of remifentanil or sufentanil and patient-controlled analgesia (PCA) with sufentanil or morphine for pain relief during ESWL. MATERIALS AND METHODS In a double blind, randomized clinical trial, ...

BACKGROUND The management of procedural pain in children ranges from physical restraint to pharmacological interventions. Pediatric formulations that permit accurate dosing, are accepted by children and a have a rapid onset of analgesia are lacking. OBJECTIVES To investigate a pediatric formulation of intranasal sufentanil 0.5 mcg·kg(-1) and ketamine 0.5 mg·kg(-1) for procedural pain and to c...

INTRODUCTION Acute pain is a common complication following cesarean section under general anesthesia. Post-cesarean section pain management is important for both the mother and the newborn. This study compared the effects of patient-controlled intravenous analgesia (PCIA) using sufentanil or tramadol on postoperative pain control and initiation time of lactation in patients who underwent cesare...

BACKGROUND There is an ongoing debate whether opioids when used for intra-operative analgesia may enhance post-operative pain. We studied the effect of two different intra-operative dosings of sufentanil on post-operative morphine consumption, pain and hyperalgesia after cardiac anaesthesia. METHODS Forty-two male patients (age: 48-74 years) undergoing first-time coronary artery bypass graft ...

this study aimed to observe the protective effects of sufentanil pretreatment on rat cerebral injury during cardiopulmonary bypass (cpb) and to explore the underlying mechanism. twenty-four male adult sprague dawley (sd) rats were divided into 4 groups. then, the rat cpb model was established. a 14g trocar was inserted into the atrium dextrum. for rats in s1 and s5 groups, sufentanil (1 µg•kg-1...

At intravenous dosages of ≥8 mcg/kg, sufentanil produces hypnosis and anesthesia without the use of additional anesthetic agents. A deep level of anesthesia is maintained at these dosages, as demonstrated by EEG patterns. Dosages of up to 25 mcg/kg attenuate the sympathetic response to surgical stress. The catecholamine response, particularly norepinephrine, is further attenuated at doses of su...

BACKGROUND Coughing, hypertension, tachycardia, and even laryngospasm can occur due to airway irritation during emergence from anesthesia. We investigated the effect of maintaining a sufentanil infusion during emergence from anesthesia by evaluating the incidence of cough and recovery profiles at extubation. METHODS In total, eighty-four patients undergoing an elective laparoscopic hysterecto...

Epidural injection of hydroxyethyl starch may be a suitable alternative for treatment of post-dural puncture headache (PDPH) if epidural blood patch is contraindicated. We reported eight consecutive female patients with accidental dural puncture (ADP), among whom prophylactic or therapeutic epidural injection of hydroxyethyl starch was performed. Prophylactic epidural injection of hydroxyethyl ...