Lamb wave time reversal method is a new and tempting baseline-free damage detection technique for structural health monitoring. With this method, certain types of damage can be detected without baseline data. However, the application of this method to thin-wall structures is complicated by the existence of at least two Lamb wave modes at any given frequency, and by the dispersion nature of the ...

Our laboratory has been utilizing the Escherichia coli outer membrane protein LamB to study the mechanism of protein localization. Various lines of evidence suggest that, in addition to a signal sequence, regions within the mature protein are required for efficient localization. In particular, studies using LamB-LacZ hybrid proteins have identified regions between amino acids 27 and 49 of matur...

The replicative responses of suckling and adult rat hepatocytes in primary culture to growth-stimulating factors were compared. By addition of L-proline alone, the [3H]-thymidine labeling of suckling rat hepatocytes was dramatically enhanced, but that of adult ones was not. Epidermal growth factor (EGF), insulin, triiodothyronine (T3) and glucagon also enhanced the labeling of suckling rat hepa...

| Damage detection using guided Lamb waves is an important tool in Structural health Monitoring. In this paper, we outline a method of obtaining Lamb wave modes in composite structures using two dimensional Spectral Finite Elements. Using this approach, Lamb wave dispersion curves are obtained for laminated composite structures with different fibre orientation. These propagating Lamb wave modes...

We study the survival of a single diffusing lamb on the positive half line in the presence of N diffusing lions to the right of the lamb and a haven at x = 0. If the lamb reaches this haven before meeting any lion, the lamb survives. We investigate the survival probability of the lamb, SN (x,L), as a function of N and the respective initial positions of the lamb and the lions, x and L. We deter...

Signal sequences function in protein targeting to and translocation across the endoplasmic reticulum membrane. To investigate the structural requirements for signal sequence function, chimeras of the Escherichia coli LamB signal peptide and prolactin were prepared. The LamB signal peptide was chosen by virtue of the extensive biophysical and biological characterization of its activity. In vitro...

Lactation is the most energy demanding part of parental care in mammals, so parent-offspring conflict arises over milk provided by the mother. In some species females commonly become pregnant shortly after parturition of previous young. This further intensifies mother-offspring conflict due to concurrent pregnancy and lactation. In equids it has been well established that pregnant females wean ...

The appearance of newly induced LamB protein at the cell surface of Escherichia coli was followed topographically by immuno-electron microscopy. LamB protein was induced in E. coli wild-type or lac-lamB cells for a short period of time (4 to 6 min), such that the overall level of LamB protein in induced cells was at least twofold higher than that in uninduced cells. Antibodies bound to LamB pro...