Subcutaneous injection is an important route of administration for therapeutic proteins that provides several advantages over other modes of parenteral delivery. Despite extensive clinical use, the exact mechanism underlying subcutaneous absorption of proteins is not completely understood, and the accuracy of prediction of absorption of biotherapeutics in humans remains unsatisfactory. This rev...

This work presents a study for tackling transient faults at the RT-level and outlines the techniques devised and implemented to speed-up fault-injection campaigns, detecting the equivalences and dominancies between faults in order to collapse them. Experimental results are provided on an industrial case study, demonstrating the effectiveness of the approach.

how to cite this article: toopchizadeh v, barzegar m, habibzadeh a. sciatic nerve injection palsy in children, electrophysiologic pattern and outcome: a case series study. iran j child neurol. summer 2015;9(3):69-72. abstract sciatic nerve injury is one of the frequent mononeuropathies in children that occurs due to different causes such as nerve compression, trauma and stretch during surgery. ...

background: testis tissue xenografting and the resultant sperm in a xenograft may provide a unique approach to rescue the genetic material of males that die prematurely and is a model for the study of human spermatogenesis and can represent an alternative approach for fertility preservation in cancer patients. this study was aimed to evaluate the xenogenic dog sperm in formation of male pronucl...

background: pregnancy is a successful transplantation. the factors evading rejection of the fetus are poorly understood. recently an interest has grown, in hla-g molecules as one of these factors. since these antigens are mainly expressed on the surface of cytotro-phoblasts that are in direct contact with maternal tissues, it has been suggested that these molecules may have a role in induction ...

this prospective study aimed to compare the intraosseous (io) and intravenous (iv) effects of propofol on selected blood parameters and physiological variables during general anesthesia in rabbits. thirty new zealand white rabbits were studied. six rabbits received iv propofol (group 1) and another 6 rabbits, were injected propofol intraosseously (group 2) for 30 minutes (experimental groups). ...

results sixty patients completed the study. patients in the hydrocortisone group had no statistically significant abdominal and shoulder pain scores compared to the bupivacaine group. the patients were similar regarding postoperative analgesic requirements, return of bowel function, nausea and vomiting. no adverse effect was detected in either group. background postoperative pain is a major com...

melasma is a common acquired skin disorder. while different treatments are currently being used, in many cases it is refractory to treatment. according to the effects of topical steroids in decreasing skin pigmentation, we studied the efficacy of this new method for treatment of melasma. a total of 42 women with facial melasma, admitted to the department of dermatology of hamadan, were enrolled...