Myocardial perfusion imaging (MPI) utilizes an intravenously administered radiopharmaceutical to depict the distribution of nutritional blood flow in the myocardium. Perfusion imaging identifies areas of reduced myocardial blood flow associated with ischemia or scar. The relative regional distribution of perfusion can be assessed at rest, cardiovascular stress, or both. Imaging can also be perf...

Background: Left ventricular mechanical dyssynchrony (LVMD) can be induced after stress test. However, no studies have compared the influence of different stress‑inducing methods on LVMD parameters. Aims: The aim study was to determine whether there is a difference between exercise and adenosine triphosphate (ATP) tests in terms changes parameters assessed using gated single‑photon emission com...

BACKGROUND Coronary artery disease can develop prematurely and is the leading cause of death among diabetics, making noninvasive risk stratification desirable. METHODS AND RESULTS Patients with symptoms of coronary artery disease who were undergoing stress myocardial perfusion imaging (MPI) from 5 centers were prospectively followed (2.5+/-1.5 years) for the subsequent occurrence of cardiac d...

OBJECTIVES Due to the frequent use of coronary angiography the awareness of Takotsubo stress cardiomyopathy (TSC) has increased although the exact pathophysiology of TSC is still largely unknown. Our objective was to investigate the effects of mental stress on myocardial function, heart rate variability (HRV) and salivary cortisol (SC) in TSC patients. DESIGN This study is a case-control stud...

Conventional noninvasive methods of evaluation of individuals with suspected coronary artery disease (CAD) have relied on functional testing by an array of modalities, including exercise treadmill testing, stress echocardiography and myocardial perfusion imaging (MPI) with single-photon emission computed tomography (SPECT),1 or positronemission tomography (PET).2 In their most commonly used app...

Vasodilator stress myocardial perfusion imaging (MPI) accounts for up to 50% of all stress MPI studies performed in the U.S. In 2008, the Food and Drug Administration approved regadenoson for stress testing in conjunction with MPI. Regadenoson, unlike adenosine, is a selective A(2A) agonist that is given as an intravenous bolus at a fixed dose, with less undesirable side effects including atrio...

BACKGROUND Although single photon emission computed tomography (SPECT) and positron emission tomography (PET) myocardial perfusion imaging (MPI) have evolved considerably over the last decade, there is no recent comparison of diagnostic performance. This study was designed to assess relative image quality, interpretive confidence, and diagnostic accuracy by use of contemporary technology and pr...

It has been quite some time since a new myocardial perfusion agent for radionuclide imaging was introduced into clinical practice. For more than 30 years, rest and stress myocardial perfusion imaging (MPI), employing first planar and then single photon emission computed tomography (SPECT) technology, have been performed with thallium201, Tc-99m sestamibi and Tc-99m tetrofosmin. MPI with these a...

Abstract Funding Acknowledgements Type of funding sources: None. Introduction Data supporting the role stress test myocardial perfusion imaging (MPI) before non-cardiac surgery (NCS) are sparse and out date. In particular, there is no specific evidence on use cardiac magnetic resonance (sCMR) in this setting. The aim present study was to evaluate impact MPI with sCMR single-photon emission comp...