Translational leakiness (i.e., nonspecific suppression) of nonsense mutants of bacteriophage T4 is increased in cells of certain streptomycin-resistant strains previously grown in the presence of streptomycin. Concomitantly, ribosomes extracted from these streptomycin-grown cells possess a high level of misreading. Increased suppression ability as well as ribosomes that highly misread accumulat...

Four cases of streptomycin stomatiti are presented together with three cases of eczematous dermatitis of the hands and feet coincident with streptomycin therapy, and attention is called to association of stomatitis with a vulvar mycotic lesion in one instzmce and Concomitant stomatitis with severe trichophytoid lesions of hands and feet in another. While the over-all series of treatment with st...

Ninety-five streptomycin-nonproducing mutants derived from Streptomyces griseus FT-1 by UV-irradiation could be classified into major two classes by cosynthesis tests. Class I mutants (42 strains) were mutants blocked in the pathway of streptomycin biosynthesis while class II mutants (49 strains) required a factor for streptomycin biosynthesis which was excreted by the parental or class I mutan...

in the present study, the effect of intrauterine infusion of zataria multiflora extract on the clinical endometritis was investigated. vaginal examination, transrectal palpation and ultrasonography were used to inspect the genital tract at 30-40 days in milk and two weeks later the same approach was applied. cows with clinical endometritis were randomly divided into three treatment groups: z. m...

Molecular characterization of a streptomycin-dependent mutant of Mycobacterium tuberculosis revealed the presence of a novel mutation in the rrs gene encoding 16S rRNA. Insertion of an additional cytosine in the 530 loop of 16S rRNA, a region known to be involved in streptomycin susceptibility and resistance, was associated with streptomycin dependence.