Cardiac progenitor cells (CPCs) have rapidly advanced to clinical trials, yet little is known regarding their interaction with the microenvironment. Signaling cues present in the microenvironment change with development and disease. This work aims to assess the influence of two distinct signaling moieties on CPCs: cyclic biaxial strain and extracellular matrix. We evaluate four endpoints for im...

Structural phase transitions between semiconductors and topological insulators have rich applications in nanoelectronics but are rarely found two-dimensional (2D) materials. In this work, by combining ab initio computations evolutionary structure search, we investigate two stable 2D forms of gold(I) telluride (${\mathrm{Au}}_{2}\mathrm{Te}$) with square symmetry, noted as s(I)- s(II)-${\mathrm{...

Complete DNA sequences of the small subunit ribosomal RNA (SSUrRNA) gene and partial sequences of three other loci were obtained from three variant-type and three classic-type Plasmodium ovale isolates from Southeast Asia and compared with GenBank-available data. Three different SSUrRNA sequences (Pov 1-3) were found in each variant-type isolate, and two different SSUrRNA sequences (Poc 1-2) in...

We developed PCR-based assays to distinguish a human pathogenic strain of Anaplasma phagocytophilum, Ap-ha, from Ap-variant 1, a strain not associated with human infection. The assays were validated on A. phagocytophilum-infected black-legged ticks (Ixodes scapularis) collected in Canada. The relative prevalence of these 2 strains in I. scapularis ticks differed among geographic regions.

An fljB-negative, multidrug-resistant Salmonella enterica serovar 4,5,12:i:2 phage type DT U302 strain (resistant to ampicillin, chloramphenicol, sulfonamide, gentamicin, streptomycin, tetracycline, and sulfamethoxazole-trimethoprim) emerged and spread in Spain in 1997. Sequences specific for Salmonella serovar Typhimurium and phage type DT 104 and U302 were present in this atypical Salmonella ...

This is the announcement of a draft genome sequence of Coxiella burnetii strain Leningrad-2, phase I. The strain, which is mildly virulent in infected guinea pigs, was isolated in 1957 from the blood of a patient with acute Q fever in Leningrad (now Saint Petersburg), Russia.

We use a multiscale approach to analyze adiabatic shear bands in a tungsten heavy alloy particulate composite deformed in plane strain tension at a nominal strain rate of 5000/s. Fifty IJ.m diameter circular tungsten particulates are assumed to be randomly distributed and perfectly bonded to the nickel-iron matrix. The volume fraction of particulates equals 50%. We first analyze transient coupl...