Strabismus has been known to have a significant genetic component, but the mode of inheritance and the identity of the relevant genes have been enigmatic. This paper reports linkage analysis of nonsyndromic strabismus. The principal results of this study are: (i) the demonstrated feasibility of identifying and recruiting large families in which multiple members have (or had) strabismus; (ii) th...

BACKGROUND Patients with strabismus experience visual dysfunction, self-image disorders, low self-esteem, and social and emotional barriers, which adversely influence their health-related quality of life (HRQoL). Currently no strabismus-specific questionnaire is available in China to identify patients' quality of life and to evaluate the effectiveness of strabismus treatment. The aims of the pr...

INTRODUCTION In congenital strabismus, sensory adaptations occur hampering the correct development of normal binocular vision. The aim of this study is to investigate if patients with congenital or early onset exotropic or esotropic strabismus adopt different walking strategies with respect to healthy subjects. Our hypothesis is that the abnormal binocular cooperation, occurring in patients wit...

The work is devoted to one of the most relevant problems ophthalmology and neurophysiology which study interhemispheric interactions in children with ophthalmopathology. purpose this lateral phenotypes Patients methods . 374 6–15 years old were observed: 1) 160 non-paralytic strabismus; 2) 111 organic pathology retina optic nerve; 3) 103 control group (without ophthalmopathology). phenotype (LP...

PURPOSE. To determine the prevalence of amblyopia and strabismus in young Singaporean Chinese children. METHODS. Enrolled in the study were 3009 Singaporean children, aged 6 to 72 months. All underwent complete eye examinations and cycloplegic refraction. Visual acuity (VA) was measured with a logMAR chart when possible and the Sheridan-Gardner test when not. Strabismus was defined as any manif...

PURPOSE To assess the validity of a novel, simplified, noninvasive test for strabismus using video goggles. DESIGN Cross-sectional method comparison study in which the new test, the strabismus video goggles, is compared with the existing reference standard, the Hess screen test. PARTICIPANTS We studied 41 adult and child patients aged ≥6 years with ocular misalignment owing to congenital or...