OBJECTIVE Upper gastrointestinal (UGI) bleeding is one of the most life-threatening complications, in up to 25% of persons with hemophilia (PWH). Recurrent bleeding is common and can be caused by the Helicobacter pylori infection. Our aim was to evaluate the role of H. pylori infection in UGI bleeding in PWH. MATERIAL AND METHODS Ninety patients with hereditary bleeding disorders, 30 patients...

OBJECTIVE To determine the association of Helicobacter pylori infection in patients presenting with idiopathic thrombocytopenic purpura (ITP). METHODS From March 2007 to March 2008, thirty adult patients with ITP and 30 age and sex matched healthy controls were investigated for the presence of H. pylori infection by Helicobacter pylori stool antigen (HpSA) an enzyme immunoassay (EIA) based me...

BACKGROUND A number of noninvasive diagnostic tests are available to detect Helicobacter pylori infection. Data on serologic testing of children are lacking, however, and thus it remains unclear whether the serology cutoff points used for adults are appropriate for children. METHODS Serum and stool samples were obtained from 73 children who visited 5 hospitals in Japan between March 1993 and ...

A chromatographic immunoassay cholera antigen detection kit, the Cholera Spot test, was evaluated. The test was found to be specific with a sensitivity of 10(6) cfu/ml for the direct detection of V. cholerae in simulated stool specimens and 10 cfu/ml in simulated cotton-tipped swab specimens after overnight incubation in alkaline peptone water. This enables early recognition of cholera cases an...

The [(13)C]urea breath test ((13)C-UBT) and Helicobacter pylori stool antigen test (HpSA) for the diagnosis of H. pylori infection in children were validated. The sensitivity, specificity, and positive and negative predictive values were 93.8, 99.1, 97.8, and 98.0%, respectively, for the (13)C-UBT and 96.9, 100, 100, and 98.0%, respectively, for HpSA. Both tests are appropriate for diagnosing H...

Background: H. pylori is one of the most important human pathogens, infecting more than 50% of the world’s population. While over 80% of infected individuals are asymptomatic, it can lead to intestinal and extra-intestinal manifestations. Intestinal manifestations include peptic ulcer disease and some gastrointestinal malignancies. Aims of the study: We aimed in this study to determine the prev...

Background: Cryptosporidium is a protozoan parasite with worldwide distribution mainly affecting children and HIV infected individuals with low CD4 counts. The infection is self limiting in immunocompetent hosts but can be severe and persist in the immunocompromised and malnourished individuals. The aim of this study was to estimate the prevalence of Cryptosporidium infection in faeces among im...

Several important papers concerning the results of intradermal tests with the peptide antigen of helminths prepared by Yamamura's method which was designed for the extraction of tuberculin active peptide have been published. For examples, Ishii and Morisawa (1961) applied it to paragonimiasis, Yoshimura (1963) to filariasis, and Tada (1966) to gnathostomiasis. Akusawa and Tsuchiya (1965) also d...

OBJECTIVES Refugees and immigrants from developing countries settling in industrialised countries have a high prevalence of Helicobacter pylori (H. pylori). Screening these groups for H. pylori and use of eradication therapy to reduce the future burden of gastric cancer and peptic ulcer disease is not currently recommended in most countries. We investigated whether a screening and eradication a...