The endogenous noradrenaline concentration, fractional turnover, half-life, and turnover rate of tritiated ((3)H) noradrenaline were determined in the oesophagus, non-glandular and glandular portions of the stomach, duodenum, jejunum, ileum, and colon of the rat. The highest concentration of endogenous noradrenaline was present in the duodenum and colon. The (3)H-noradrenaline fractional turnov...

Due to the optimal composition of microelements, treatment with mineral waters "Vardzia" and "Zanavi" in patients suffering from gastroduodenitis led positive dynamics clinical symptoms disease. The anti-inflammatory, analgesic anti-toxic effect was revealed, structure mucous membrane stomach duodenum significantly improved, which normalization acid-producing function growth surface epithelium ...

The molecular identity of the apical HCO3(-)-secreting transporter in gastric mucous cells remains unknown despite its essential role in preventing injury and ulcer by gastric acid. Here we report the identification of a Cl-/HCO3- exchanger that is located on apical membranes of gastric surface epithelial cells. RT-PCR studies of mouse gastrointestinal tract mRNAs demonstrated that this transpo...

With respect to the significance of duodenal extension of stomach cancer in practical surgery, 833 stomach specimens obtained by subtotal gastrectomy were examined histologically. The incidence of duodenal invasion was 18.1 per cent (151 cases) as a whole but as high as 37.0 per cent in the 135 cases in which the stomach tumors were 1 cm or less distant from the pyloric ring. Of the cases with ...

Gastric HCO3(-) transport (basal) studied in isolated amphibian mucosa and mammalian stomach in vivo amounts to 2-10% of maximal H+ secretion. Duodenal mucosa, devoid of Brunner's glands, transports HCO3(-) at a greater rate (per unit surface area) than either stomach or jejunum in vitro and in vivo. Gastric (but not duodenal) HCO3(-) transport is stimulated by dibutyryl cGMP, carbachol, and ch...

A recent study of the physiology of flow through the sphincter of Oddi (Wyatt, 1967) indicated that amongst other factors gastric peristalsis was related to changes of resistance at the sphincter. This was especially notable when food was present in the stomach. Electrical stimuli leading to contraction of the gastric antrum often resulted in relaxation of the sphincter with increased flow thro...

Gastrointestinal melanoma (GIM) is occasionally observed in general practice. We report a case of melanoma dispersed diffusely in the stomach and duodenum with no skin involvement.

ried out in a local hospital revealed expansion both within and outside the liver bile duct but found no stone or neoplasm. Then, she was referred to our hospital where physical examination revealed epigastric tenderness while the liver, spleen, and superficial lymph nodes were not palpable. The patient’s main laboratory data showed no abnormality except for a slight elevation of tumor markers ...