Suppression of endogenous hormone production by gonadotrophin-releasing hormone (GnRH) agonists followed by controlled ovarian hyperstimulation (COH) with human gonadotrophins, especially the so-called 'long protocol' has developed from second-line into first-line therapy. Due to this attitude premature luteinization can be safely avoided, enhancing therapeutic efficacy. Recombinant preparation...

introduction: mechanical stimulation of human mesenchymal stem cells has demonstrated changes in many cell behaviours such as adhesion, migration, growth and differentiation through mechanotransductive pathways. these include experiments on effect of nanotopography 1, shear stress, stiffness of extracellular matrix 2, strain, stress and acoustic wave energy 3 on cells. in this research we were ...

In Brief High-definition transcranial direct current stimulation (HD-tDCS) of brain areas related to pain processing may provide analgesic effects evident in the sensory detection and thresholds. The somatosensory sensitivity was assessed after HD-tDCS targeting primary motor cortex (M1) and/or dorsolateral prefrontal (DLPFC). Eighty-one (40 females) subjects were randomly assigned 1 4 anodal p...

OBJECTIVES We sought to develop a high-yield canine model of sudden cardiac death (SCD). BACKGROUND Because electrical stimulation is a powerful means to elicit nerve sprouting, we hypothesize that subthreshold electrical stimulation is more effective than nerve growth factor (NGF) infusion in inducing nerve sprouting and SCD in dogs with myocardial infarction (MI) and complete atrioventricul...

Learning, or more generally, plasticity may be studied using cultured networks of rat cortical neurons on multi electrode arrays. Several protocols have been proposed to affect connectivity in such networks. One of these protocols, proposed by Shahaf and Marom, aimed to train the input-output relationship of a selected connection in a network using slow electrical stimuli. Although the results ...

The protocol used for intermittent photic stimulation (IPS) may determine the likelihood of evoking a photoparoxysmal response (PPR). One-hundred and thirty-five electroencephalograms (EEGs) presenting PPRs, from 125 patients were studied in order to identify the most effective stimulation frequency to evoke a PPR and the effects of repetition of IPS on the occurrence of a PPR. Two stimulation ...

At the moment, problem of infertility does not lose its relevance. In structure this disease, violation reproductive function in women is dominant. The present study devoted to influence concomitant extragenital pathology on success assisted technology procedures. data 184 who underwent treatment by ART methods clinics Volgograd region period from 2015 2020 were analyzed. following parameters p...

OBJECTIVE To compare the two GnRH-a protocols (long GnRH-a protocol and short GnRH-a protocol) for ovarian stimulation in IVF/ICSI cycles in patients of various age ranges. METHODS A total of 5662 IVF-ET/ICSI cycles from 2010 to 2013 were retrospectively identified. The cycles were divided into two groups: a long protocol group and short protocol group. In each group, the patients were divide...

A protocol for programmed ventricular stimulation is described in which the effect of increasing stimulation current on ventricular refractoriness and arrhythmia induction was specifically examined. The protocol was evaluated prospectively in 70 patients undergoing electrophysiological study for documented or suspected ventricular arrhythmias. Programmed electrical stimulation was performed at ...

background: based on classical two-cell, two-gonadotropin theory, in the follicle, follicle-stimulating hormone (fsh) and luteinizing hormone (lh) put on their main effects on the granulosa and theca cells. lh is essential for androgens production. androgens are used for estradiol production by granulosa cells. profound suppression of lh concentrations in some normogonadotropic patients can cau...