introduction: there are controversies regarding treatment of peritonsillar abscess as a common infection of head and neck, especially for prescription of corticosteroids. according to review of articles, use of corticosteroids in management of this abscess is increasing, but more controlled and comparative studies are needed. in this clinical trial study, we evaluated corticosteroid as an adjut...

If changes in the composition of the soil microbial community alter the physiological capacity of the community then such changes may have ecosystem consequences. We examined the relationships among community composition (PLFA), microbial biomass (CFDE), substrate utilization profiles (BIOLOG), lignocellulose degrading enzyme activities (b-glucosidase, cellobiohydrolase, b-xylosidase, phenol ox...

BACKGROUND & OBJECTIVES Multiple suphphatase deficiency (MSD) is an autosomal recessive disorder affecting the post translational activation of all enzymes of the sulphatase family. To date, approximately 30 different mutations have been identified in the causative gene, sulfatase modifying factor 1 (SUMF1). We describe here the mutation analysis of a case of MSD. METHODS The proband was a fo...

Mammalian sulphatases (EC 3.1.6) are a family of enzymes that have a high degree of similarity in amino acid sequence, structure and catalytic mechanism. IDS (iduronate-2-sulphatase; EC 3.1.6.13) is a lysosomal exo-sulphatase that belongs to this protein family and is involved in the degradation of the glycosaminoglycans heparan sulphate and dermatan sulphate. An IDS deficiency causes the lysos...

Abstract-An examination was made of the effect of changes in the osmolarity and the ionic composition of the homogenizing medium on the partition of lysosomal arylsulphatase and N-acetylglucosaminidase of cerebral cortex, hypothalamus and thalamus of the rat. Sulphatase appeared to be more sensitive to hypotonicity than glucosaminidase, since a higher proportion of the sulphatase was released f...

Rabbit retinal tissue experimentally infected with Toxoplasma gondii was processed for the lysosomal enzyme aryl sulphatase. Abundant lysosomal activity was found in lysosomal bodies of the infected macrophages. There appeared to be a lack of fusion of the lysosomal bodies with the phagosomes containing the organisms. Examination of the majority of macrophage vacuoles containing trophozoites fa...

Purple urine bag syndrome (PUBS) occurs in catheterized patients with bacterial urinary infections that produce sulphatase/ phosphatase. The presence of indigo and indirubin pigments, which are tryptophan metabolites, causes the purple coloring. After antibiotic therapy, colour reverts to normal. We present a case report unusual phenomenon occurring 60-year-old woman carcinoma cervix. She did n...